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Varan Perananthan, M.D., Ph.D.

  1. Gastroenterologist
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Departments

Specialty Groups

Location

  1. Rochester, Minnesota

Languages

English

Existing patients

Dr. Varan Perananthan, M.D., Ph.D., is a Senior Associate Consultant Gastroenterologist at Mayo Clinic in Rochester, Minnesota. He specializes in esophageal diseases, with a clinical and research focus on the endoscopic management of achalasia, advanced therapeutic luminal endoscopy, complex reflux disease and strictures, and Barrett’s esophagus.

His academic work focuses on clinical outcomes after peroral endoscopic myotomy (POEM), physiologic predictors of treatment response, and technology-driven innovations in endoscopy, including imaging analytics and novel device development. Dr. Perananthan has authored peer-reviewed publications, presented at international scientific meetings, and secured competitive research funding.

Dr. Perananthan earned his medical degree from the University of New South Wales in Sydney, Australia. He completed his residency in internal medicine and fellowship training in gastroenterology and hepatology in Australia, followed by an advanced fellowship in esophageal diseases at Mayo Clinic in Rochester before joining the faculty.

  1. Achalasia
  2. Barrett's esophagus
  3. Barrett's esophagus with dysplasia
  4. Colon polyps
  5. Dysphagia
  6. Eosinophilic esophagitis
  7. Eosinophilic gastroenteritis
  8. Esophageal cancer
  9. Esophageal cyst
  10. Gastroesophageal reflux disease
  11. Lichen planus
  12. Zenker's diverticulum
  1. Colonoscopy
  2. Endoscopic dilation
  3. Endoscopic mucosal resection
  4. Esophageal manometry
  5. Esophageal reflux scan
  6. Upper endoscopy
  1. 2025
    SubSpec FellowGI - Esophageal Disease, Programs in Rochester, Mayo School of Graduate Medical Education, Mayo Clinic College of Medicine
  2. 2024
    SubSpec Fellow - Tissue Resection and Advanced Luminal InterventionWestmead Hospital
  3. 2024
    SubSpec Fellow - Advanced Esophageal Fellow & Visiting Medical Officer General GastroenterologyAlfred Hospital
  4. 2024
    Ph.D.Department of Medicine, University of Sydney
  5. 2023
    Fellow - Gastroenterology and Hepatology FellowWestmead Hospital
  6. 2022
    Fellow - Gastroenterology and Hepatology FellowThe Wollongong Hospital
  7. 2020
    Medical Registrar - Internal Medicine RegistrarConcord Repatriation General Hospital, Royal Australasian College of Physicians
  8. 2020
    MPHDepartment of Medicine, University of Sydney
  9. 2014
    MDUniversity of New South Wales

Awards and honors

  1. 2025
    Henry Bockus Travel Grant Award World Gastroenterology Organization
  2. 2025
    Tom DeMeester & Don Castell Scholarship Foregut Disease Foundation
  3. 2022
    Royal Australasian College of Physicians Trainee Research PrizeRoyal Australasian College of Physicians
  4. 2021
    Clinical Pharmacology Trainee Research Prize Australasian Society of Clinical and Experimental Pharmacologists and Toxicologists
  5. 2020
    Clinical Pharmacology Trainee Research PrizeAustralasian Society of Clinical and Experimental Pharmacologists and Toxicologists

Professional memberships

  1. 2025 - present
    MemberAmerican Society for Gastrointestinal Endoscopy
  2. 2024 - present
    MemberAmerican Gastroenterological Association
  3. 2023 - present
    PhysicianRoyal Australasian College of Physicians
  4. 2021 - present
    MemberGastroenterology Society of Australia

Publications