Amir B. Orandi, M.D.

Dr. Amir Orandi is a pediatric rheumatologist at Mayo Clinic in Rochester, Minnesota, where he cares for children and adolescents with autoimmune and autoinflammatory conditions. Dr. Orandi partners with families to provide individualized care for rheumatologic diseases that can impact growth, development and quality of life. He has a particular clinical interest in juvenile dermatomyositis, especially the complication of calcinosis, and is committed to advancing treatments and improving outcomes for children with these conditions.

Dr. Orandi is board-certified in general pediatrics and pediatric rheumatology. In addition to his clinical work, he is active in medical education, training medical students, pediatric residents and future rheumatology specialists.

Conditions treated

Dr. Orandi provides care for children with a wide range of autoimmune and inflammatory conditions. His areas of expertise include:

• Juvenile idiopathic arthritis: Comprehensive care for inflammatory joint disease in children
• Juvenile dermatomyositis: Special focus on complications such as calcinosis
• Autoinflammatory diseases: Evaluation and management of periodic fever and related syndromes
• Lupus and lupus nephritis: Diagnosis and long-term care for systemic and renal involvement
• Mixed connective tissue disease, scleroderma and morphea: Management of complex multi-system disorders
• Vasculitis: Care for children with small, medium and large vessel vasculitides
• Uveitis: Treatment aimed at preserving vision and preventing complications
• Chronic recurrent multifocal osteomyelitis: Coordinated orthopedic and rheumatologic care

Research and expertise

Dr. Orandi's academic focus includes juvenile dermatomyositis and its complications, particularly calcinosis. He has contributed to multicenter research efforts to improve understanding and management of pediatric inflammatory diseases. He actively participates in international study groups and serves as a reviewer for several pediatric rheumatology journals. In addition, Dr. Orandi serves in leadership and educational roles at Mayo Clinic, helping shape pediatric rheumatology training programs.