Kappa and lambda free light chain test

الأقسام والتخصصات

تضم Mayo Clinic أكبر العيادات وأكثرها خبرة في الولايات المتحدة الأمريكية، وتوجد فروعها في ولاية أريزونا وفلوريدا ومينيسوتا. ويتعاون كادرها الماهر المكون من عدة تخصصات لضمان تقديم علاج ناجح ورعاية عالية الجودة.

الأبحاث

Mayo Clinic researchers study immunoglobulin light chains in plasma cell disorders such as:

• Monoclonal gammopathy of undetermined significance (MGUS).
• Multiple myeloma, which is a type of blood cancer.
• Light chain amyloidosis.

Their work includes using mass spectrometry to examine immunoglobulins in blood, urine and tissue, with the goal of improving diagnosis, prognosis and monitoring. Researchers also study biomarkers that may help show how monoclonal gammopathies develop or progress.

Mayo Clinic research also focuses on how light chains affect organs, especially the kidneys. Investigators are developing noninvasive methods, including urinary exosome testing, to detect kidney involvement in light chain amyloidosis and are working to improve diagnostic tests and measures of treatment response in kidney diseases related to monoclonal gammopathy.

Publications

See a list of publications about kappa and gamma free light chains by Mayo Clinic doctors on PubMed, a service of the National Library of Medicine.

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