Diagnosis

Tests used to help make a diagnosis of gangrene include:

  • Blood tests. An abnormally elevated white blood cell count often indicates the presence of an infection. Your doctor might also perform blood tests to look for the presence of certain bacteria or other germs.
  • Imaging tests. An X-ray, a computerized tomography (CT) scan or a magnetic resonance imaging (MRI) scan can be used to view interior body structures, such as your internal organs, blood vessels or bones, and assess the extent to which gangrene has spread. These types of tests can also help your doctor see any gas that is present under your skin.

    An arteriogram is an imaging test used to visualize your arteries. During this test, dye is injected into your bloodstream and X-ray pictures are taken to determine how well blood is flowing through your arteries. An arteriogram can help your doctor find out whether any of your arteries are blocked.

  • Surgery. Surgery may be performed to determine the extent to which gangrene has spread within your body.
  • Fluid or tissue culture. A culture of the fluid from a blister on your skin may be examined for the bacterium Clostridium perfringens, a common cause of gas gangrene, or your doctor may look at a tissue sample under a microscope for signs of cell death.
July 13, 2017
References
  1. Usatine RP, et al., eds. Dry gangrene. In: The Color Atlas of Family Medicine. 2nd ed. New York, N.Y.: McGraw-Hill; 2013. http://accessmedicine.mhmedical.com. Accessed March 13, 2017.
  2. Stevens D, et al. Clostridial myonecrosis. http://www.uptodate.com/home. Accessed March 13, 2017.
  3. Bryant A, et al., eds. Gas gangrene and other clostridial infections. In: Harrison's Principles of Internal Medicine. 19th ed. New York, N.Y.: McGraw-Hill; 2014. http://accessmedicine.mhmedical.com/content.aspx?bookid=1130§ionid=79735535. Accessed March 13, 2017.
  4. Conly J., eds. Soft tissue infections. In: Principles of Critical Care. 4th ed. New York, N.Y.: McGraw-Hill; 2014. http://accessmedicine.mhmedical.com. Accessed March 13, 2017.
  5. Tubbs RJ, et al., eds. Extremity conditions. In: The Atlas of Emergency Medicine. 4th ed. New York, N.Y.: McGraw-Hill; 2016. http://accessmedicine.mhmedical.com. Accessed March 13, 2017.
  6. Lipworth AD, et al., eds. Necrotizing soft tissue infections: Necrotizing fasciitis, gangrenous cellulitis, and myonecrosis. In: Fitzpatrick's Dermatology in General Medicine. 8th ed. New York, N.Y.: McGraw-Hill; 2016. http://accessmedicine.mhmedical.com. Accessed March 13, 2017.
  7. Schwarts BS, et al., eds. Bacterial and chlamydial infections. In: Current Medical Diagnosis & Treatment 2017. 56th ed. New York, N.Y.: McGraw-Hill; 2017. http://accessmedicine.mhmedical.com. Accessed March 13, 2017.
  8. Ogle JW et al., eds. Infections: Bacterial and spirochetal. In: Current Diagnosis & Treatment Pediatrics. 23rd ed. New York, NY: McGraw-Hill; 2016. http://accessmedicine.mhmedical.com. Accessed March 13, 2017.
  9. Mechem CC, et al. Hyperbaric oxygen therapy. http://www.uptodate.com/home. Accessed March 27, 2017.