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  1. Ruqin Chen, M.D., M.B.

    Ruqin Chen, M.D., M.B.

    1. Oncologist
    1. Jacksonville, FL
    擅长领域:

    Chemotherapy, Immunotherapy, Targeted drug therapy, Hormone therapy for prostate cancer, Kidney cancer, Prostate cancer..., Bladder cancer, Melanoma

研究

With state-of-the-art lab space and leading physician-researchers in the Department of Oncology, the Department of Urology and throughout Mayo Clinic, we are committed to improving options for patients with urologic cancers such as prostate cancer. We partner with our patients to achieve optimal care for these cancers. We conduct research to better understand cancer biology and to find ways to better target cancer cells with both surgical and nonsurgical approaches. Mayo Clinic also offers ongoing clinical trials that explore methods to reduce hormone therapy use and overcome hormone therapy side effects for some people with prostate cancer.

Prostate cancer research is conducted in coordination with Mayo Clinic Comprehensive Cancer Center. Mayo Clinic Comprehensive Cancer Center receives funding from the National Cancer Institute and is designated as a comprehensive cancer center. This designation recognizes the institution's scientific excellence and multidisciplinary resources focused on cancer prevention, diagnosis and treatment.

Publications

See a list of publications about hormone therapy for prostate cancer by Mayo Clinic doctors on PubMed, a service of the National Library of Medicine.

July 15, 2025
  1. Prostate cancer. National Comprehensive Cancer Network. https://www.nccn.org/guidelines/guidelines-detail?category=1&id=1459. Accessed May 27, 2025.
  2. Prostate cancer: Early stage. National Comprehensive Cancer Network. https://www.nccn.org/patientresources/patient-resources/guidelines-for-patients/guidelines-for-patients-details?patientGuidelineId=49. Accessed May 27, 2025.
  3. Lowrance W, et al. Updates to advanced prostate cancer: AUA/SUO guideline (2023). The Journal of Urology. 2023; doi:10.1097/JU.0000000000003452.
  4. Hormone therapy for prostate cancer. National Cancer Institute. https://www.cancer.gov/types/prostate/prostate-hormone-therapy-fact-sheet. Accessed May 27, 2025.
  5. Smith MR. Side effects of androgen deprivation therapy. https://www.uptodate.com/contents/search. Accessed Feb. 16, 2023.
  6. Dmochowski RR, et al., eds. Management of recurrent and newly metastatic prostate cancer. In: Campbell-Walsh-Wein Urology. 13th ed. Elsevier; 2026. https://www.clinicalkey.com. Accessed May 27, 2025.
  7. Hussain M, et al. Metastatic hormone-sensitive prostate cancer and combination treatment outcomes: A review. JAMA Oncology. 2024; doi:10.1001/jamaoncol.2024.0591.
  8. Hamid AA, et al. Metastatic hormone-sensitive prostate cancer: Toward an era of adaptive and personalized treatment. American Society of Clinical Oncology Educational Book. 2023; doi:10.1200/EDBK_390166.
  9. Gudenkauf LM, et al. Balancing hormone therapy: Mitigating adverse effects of androgen-deprivation therapy and exploring alternatives in prostate cancer management. American Society of Clinical Oncology Educational Book. 2024; doi:10.1200/EDBK_433126.
  10. Boue A, et al. Does hormone therapy impact cognition in patients with prostate cancer? A systematic review and meta-analysis. Cancer. 2024; doi:10.1002/cncr.35210.
  11. Solanki AJ, et al. A practical guide for assessing and managing cardiovascular risk during androgen-deprivation therapy in patients with prostate cancer. Cancer. 2024; doi:10.1002/cncr.35285.
  12. Lupron (prescribing information). AbbVie Inc.; 2023. https://www.lupron.com/pi.html. Accessed June 6, 2025.
  13. Zoladex (prescribing information). AstraZeneca Pharmaceuticals LP; 2023. https://www.zoladexhcp.com/dosing-administration/. Accessed June 6, 2025.
  14. Vaz R, et al. Testicular cancer — Surgical treatment. Frontiers in Endocrinology. 2019; doi:10.3389/fendo.2019.00308.
  15. Dawson NA, et al. Overview of the treatment of castration-resistant prostate cancer (CRPC). https://www.uptodate.com/contents/search. Accessed June 12, 2025.
  16. Hormone therapy for prostate cancer. National Cancer Institute. https://www.cancer.gov/types/prostate/prostate-hormone-therapy-fact-sheet. Accessed June 12, 2025.
  17. Harris WP, et al. Androgen deprivation therapy: Progress in understanding mechanisms of resistance and optimizing androgen depletion. Nature Clinical Practice Urology; 2009. doi:10.1038/ncpuro1296.
  18. Cancer stat facts: Prostate cancer. National Cancer Institute. https://seer.cancer.gov/statfacts/html/prost.html. Accessed June 12, 2025.
  19. Harris KM. Allscripts EPSi. Mayo Clinic. April 23, 2024.
  20. Questions to ask about prostate cancer. American Cancer Society. https://www.cancer.org/cancer/types/prostate-cancer/detection-diagnosis-staging/talking-with-doctor.html. Accessed June 18, 2025.
  21. Questions to ask about cancer care. National Comprehensive Cancer Network. https://www.nccn.org/patientresources/patient-resources/resources-for-patients-caregivers/questions-to-ask-about-cancer. Accessed June 18, 2025.
  22. Anheuser P, et al. Complications associated with inguinal orchiectomy and scrotal orchiectomy. Urologe. 2014; doi:10.1007/s00120-014-3487-3.
  23. Hormone therapy for advanced prostate cancer. Mayo Clinic Press. https://mcpress.mayoclinic.org/cancer/hormone-therapy-for-advanced-prostate-cancer. Accessed June 18, 2025.