Li-Fraumeni syndrome

科室与专家门诊

妙佑医疗国际是美国规模最大、经验最丰富的医疗机构之一，在亚利桑那州、佛罗里达州和明尼苏达州都有院区。医务人员掌握数几十种专业技能，齐心协力，确保高品质治疗与成功康复。

研究

Mayo Clinic researchers are studying Li-Fraumeni syndrome and other inherited cancer conditions to improve genetic testing, cancer detection and prevention. Recent Mayo Clinic research has examined mosaic Li-Fraumeni syndrome. This includes how testing different tissues may help show if a TP53 gene change is present in many parts of the body or is limited to blood cells. Mayo Clinic researchers also study rare genetic conditions through Clinical Genomics and collect donated samples and health information in biobanks to better understand how genes affect health and cancer risk.

Researchers also are studying how cancers may begin in people with inherited cancer risk. For example, Mayo Clinic researchers used cells donated by a patient with another inherited cancer condition, as well as Li-Fraumeni syndrome, to look for very early changes in fallopian tube cells that might lead to ovarian cancer. A Mayo Clinic living fallopian tube biobank includes samples from people with inherited cancer-related gene changes and is being used to study earlier cancer detection and ways to lower cancer risk.

Publications

See a list of publications about Li-Fraumeni syndrome by Mayo Clinic doctors on PubMed, a service of the National Library of Medicine.

Research Profiles