Estrogen blocker therapy for breast cancer

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Displaying 1-1 out of 1 doctors available

  1. Sarah A. McLaughlin, M.D.

    Sarah A. McLaughlin, M.D.

    1. Surgical Oncologist
    1. Jacksonville, FL
    Areas of focus:

    Mastectomy, Lumpectomy, Breast surgery, Breast reconstruction, Breast cancer surgery, Oncoplastic breast-conserving sur...gery, Modified radical mastectomy, Double mastectomy, Estrogen blocker therapy for breast cancer, Breast cancer, Lymphedema, Triple-positive breast cancer, High risk for breast cancer

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By Mayo Clinic Staff
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About
Aug. 28, 2026
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  1. Breast cancer. National Comprehensive Cancer Network. https://www.nccn.org/guidelines/guidelines-detail?category=1&id=1419. Accessed Aug. 3, 2026.
  2. Hormone therapy for breast cancer. National Cancer Institute. https://www.cancer.gov/types/breast/treatment/hormone-therapy. Accessed Aug. 3, 2026.
  3. Allison KH, et al. Estrogen and progesterone receptor testing in breast cancer: ASCO/CAP guideline update. Journal of Clinical Oncology. 2020; doi:10.1200/JCO.19.02309.
  4. Burstein HJ, et al. Adjuvant endocrine therapy for women with hormone receptor-positive breast cancer: ASCO clinical practice guideline focused update. Journal of Clinical Oncology. 2019; doi:10.1200/JCO.18.01160.
  5. Burstein HJ, et al. Endocrine treatment and targeted therapy for hormone receptor-positive, human epidermal growth factor receptor 2-negative metastatic breast cancer: ASCO guideline update. Journal of Clinical Oncology. 2021; doi:10.1200/JCO.21.01392.
  6. Papakonstantinou A, et al. Adjuvant endocrine treatment strategies for non-metastatic breast cancer: A network meta-analysis. eClinicalMedicine. 2025; doi:10.1016/j.eclinm.2025.103116.
  7. Pala L, et al. Tailoring the optimal duration of extended adjuvant endocrine therapy in patients with early-stage breast cancer: A systematic review and meta-analysis of randomized clinical trials. The Breast. 2023; doi:10.1016/j.breast.2023.02.012.
  8. Klimberg VS, et al., eds. Systemic therapy of hormone-sensitive HER2-negative breast cancer: Adjuvant and neoadjuvant. In: Bland and Copeland's The Breast: Comprehensive Management of Benign and Malignant Diseases. 6th ed. Elsevier; 2024. https://www.clinicalkey.com. Accessed Aug. 3, 2026.
  9. Zuo H, et al. Impact of early discontinuation of adjuvant endocrine therapy on survival in breast cancer: A target trial emulation. European Journal of Cancer. 2025; doi:10.1016/j.ejca.2025.115665.
  10. Eliassen FM, et al. Importance of endocrine treatment adherence and persistence in breast cancer survivorship: A systematic review. BMC Cancer. 2023; doi:10.1186/s12885-023-11122-8.
  11. AskMayoExpert. Invasive breast cancer: Survivorship. Mayo Clinic; 2021.
  12. Gradishar WJ, et al. NCCN Clinical Practice Guidelines in Oncology: Breast Cancer, Version 3.2024. Journal of the National Comprehensive Cancer Network. 2024; doi:10.6004/jnccn.2024.0035.
  13. Gradishar WJ, et al. NCCN Guidelines Insights: Breast Cancer, Version 5.2025. Journal of the National Comprehensive Cancer Network. 2025; doi:10.6004/jnccn.2025.0053.
  14. Ma Y, et al. Symptom experience in endocrine therapy for breast cancer patients: A qualitative systematic review and meta-synthesis. Asia-Pacific Journal of Oncology Nursing. 2024; doi:10.1016/j.apjon.2023.100364.
  15. Orserdu (prescribing information). Stemline Therapeutics Inc.; 2026. https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=aa66ae5c-2bd2-4444-8178-b55651e054ef. Accessed Aug. 10, 2026.
  16. Medical review (expert opinion). Mayo Clinic. Aug. 7, 2026.
  17. Campone M, et al. Vepdegestrant, a PROTAC estrogen receptor degrader, in advanced breast cancer. New England Journal of Medicine. 2025; doi:10.1056/NEJMoa2505725.

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Estrogen blocker therapy for breast cancer