Prostate brachytherapy

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Mayo Clinic has one of the largest and most experienced practices in the United States, with campuses in Arizona, Florida and Minnesota. Staff skilled in dozens of specialties work together to ensure quality care and successful recovery.

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Research

Mayo Clinic researchers are studying ways to improve how well prostate brachytherapy works.

The effectiveness of permanent prostate brachytherapy depends on how the radioactive seeds are placed. Researchers at Mayo Clinic study imaging techniques to improve the results of permanent prostate brachytherapy treatment. They have conducted tests on human tissue that produce clear, 3D images of the prostate within minutes.

Cancer research is conducted in coordination with Mayo Clinic Comprehensive Cancer Center. Mayo Clinic Comprehensive Cancer Center receives funding from the National Cancer Institute and is designated as a comprehensive cancer center. This designation recognizes the institution's scientific excellence and multidisciplinary resources focused on cancer prevention, diagnosis and treatment.

Publications

See a list of publications about prostate brachytherapy by Mayo Clinic doctors on PubMed, a service of the National Library of Medicine.

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Prostate brachytherapy care at Mayo Clinic

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AboutCare at Mayo Clinic
May 13, 2026
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  1. Prostate cancer. National Comprehensive Cancer Network. https://www.nccn.org/professionals/physician_gls/default.aspx. Accessed June 9, 2025.
  2. Dmochowski RR, et al., eds. Radiation therapy for prostate cancer. In: Campbell-Walsh- Wein Urology. 13th ed. Elsevier; 2026. https://www.clinicalkey.com. Accessed June 10, 2025.
  3. What is brachytherapy? American Brachytherapy Society. https://www.americanbrachytherapy.org/resources/for-patients/what-is-brachytherapy. Accessed June 10, 2025.
  4. Eastham JA, et al. Clinically localized prostate cancer: AUA/ASTRO Guideline. Part III: Principles of radiation and future directions. Journal of Urology. 2022; doi:10.1097/JU.0000000000002759.
  5. Prostate cancer. RTAnswers. https://www.rtanswers.org/cancer-types/prostate-cancer. Accessed June 10, 2025.
  6. Roach M, et al. Brachytherapy for low-risk or favorable intermediate-risk, clinically localized prostate cancer. https://www.uptodate.com/contents/search. Accessed June 11, 2025.
  7. Penson DF. Follow-up surveillance after definitive local treatment for prostate cancer. https://www.uptodate.com/contents/search. Accessed June 11, 2025.
  8. Tepper JE, et al., eds. Prostate cancer. In: Gunderson & Tepper's Clinical Radiation Oncology. 5th ed. Elsevier; 2021. https://www.clinicalkey.com. Accessed June 11, 2025.
  9. Lazarev S, et al. Low-dose-rate brachytherapy for prostate cancer: Outcomes at >10 years of follow-up. BJU International. 2018; doi:10.1111/bju.14122.
  10. Medical review (expert opinion). Mayo Clinic. April 21, 2026.

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Prostate brachytherapy