Colon cancer surgery

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Departments and specialties

Mayo Clinic has one of the largest and most experienced practices in the United States, with campuses in Arizona, Florida and Minnesota. Staff skilled in dozens of specialties work together to ensure quality care and successful recovery.

Departments with related expertise

Areas that research this procedure

Research

Designated as a comprehensive cancer center by the National Cancer Institute, Mayo Clinic Comprehensive Cancer Center is defining new boundaries in colon cancer research.

Areas of research include:

  • Chemotherapy options after surgery. This study is finding the best chemotherapy treatment for people after surgery by checking for any remaining cancer cells, called circulating tumor DNA, in the blood.
  • MUC1 vaccine. Researchers are testing a vaccine targeting the MUC1 protein in people with a history of precancerous polyps to see if it can prevent colon cancer.
  • Endoscopy with indigo carmine. Researchers are testing the use of a blue dye mixed with standard colonoscopy prep to see if it improves polyp detection in the right colon.

Publications

See a list of publications about colon cancer by Mayo Clinic doctors on PubMed, a service of the National Library of Medicine.

By Mayo Clinic Staff

Colon cancer surgery care at Mayo Clinic

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AboutCare at Mayo Clinic
May 28, 2025
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  1. Colon cancer. National Comprehensive Cancer Network. https://www.nccn.org/guidelines/guidelines-detail?category=1&id=1428. Accessed Jan. 31, 2025.
  2. Vogel JD, et al. The American Society of Colon and Rectal Surgeons clinical practice guidelines for the management of colon cancer. Diseases of the Colon and Rectum. 2022; doi:10.1097/DCR.0000000000002323.
  3. Steele SR, et al., eds. Colon cancer surgical treatment. In: The ASCRS Textbook of Colon and Rectal Surgery. 4th ed. Springer; 2022. https://search.ebscohost.com. Accessed Jan. 31, 2025.
  4. Clark S, et al., eds. Surgery for colon cancer. In: Colorectal Surgery: A Companion to Specialist Surgical Practice. 7th ed. Elsevier; 2024. https://www.clinicalkey.com. Accessed Jan. 31, 2025.
  5. Cameron JL, et al., eds. Surgical management of colon cancer. In: Current Surgical Therapy. 14th ed. Elsevier; 2023. https://www.clinicalkey.com. Accessed Jan. 31, 2025.
  6. Hagberg C. Perioperative care of the colorectal cancer patient. In: Perioperative Care of the Cancer Patient. Elsevier; 2023. https://www.clinicalkey.com. Accessed Jan. 31, 2025.
  7. Colon cancer treatment (PDQ) — Health professional version. National Cancer Institute. https://www.cancer.gov/types/colorectal/hp/colon-treatment-pdq. Accessed Jan. 31, 2025.
  8. Treating colorectal cancer. American Cancer Society. https://www.cancer.org/cancer/types/colon-rectal-cancer/treating.html. Accessed Jan. 30, 2025.
  9. After surgery for colon cancer. Cancer Research UK. https://www.cancerresearchuk.org/about-cancer/bowel-cancer/treatment/treatment-colon/surgery-colon/after-surgery-bowel-cancer. Accessed Feb. 25, 2025.
  10. Nimmagadda R. AllScripts EPSi. Mayo Clinic. Feb. 26, 2025.
  11. Colostomy guide. American Cancer Society. https://www.cancer.org/cancer/managing-cancer/treatment-types/surgery/ostomies/colostomy.html. Accessed March 26, 2025.
  12. Enterprise colorectal and anal cancer surgical cases: 2022-2024. Mayo Clinic. March 5, 2025.
  13. Medical review (expert opinion). Mayo Clinic. March 26, 2025.

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Colon cancer surgery