Choline C-11 PET scan

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Mayo Clinic has one of the largest and most experienced practices in the United States, with campuses in Arizona, Florida and Minnesota. Staff skilled in dozens of specialties work together to ensure quality care and successful recovery.

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Research

Doctors and scientists at Mayo Clinic are studying ways to improve detection of recurrent prostate cancer, including new ways of using choline C-11 PET scans and new kinds of imaging tests. They also are studying new uses of this test for other conditions, such as hyperparathyroidism.

Cancer research is conducted in coordination with Mayo Clinic Comprehensive Cancer Center. Mayo Clinic Comprehensive Cancer Center receives funding from the National Cancer Institute and is designated as a comprehensive cancer center. This designation recognizes the institution's scientific excellence and multidisciplinary resources focused on cancer prevention, diagnosis and treatment.

Publications

See a list of publications about recurrent prostate cancer by Mayo Clinic doctors on PubMed, a service of the National Library of Medicine.

By Mayo Clinic Staff

Choline C-11 PET scan care at Mayo Clinic

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AboutCare at Mayo Clinic
March 14, 2025
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  1. Choline C 11 Injection (prescribing information). Mayo Clinic PET Radiochemistry Facility; 2024. https://www.accessdata.fda.gov/scripts/cder/daf/index.cfm?event=overview.process&ApplNo=203155. Accessed Dec. 3, 2024.
  2. Saha S, et al. C11 choline PET/CT succeeds when conventional imaging for primary hyperparathyroidism fails. Surgery. 2023; doi:10.1016/j.surg.2022.08.024.
  3. PET/CT. RadiologyInfo.org. https://www.radiologyinfo.org/en/info/pet. Accessed Nov. 4, 2024.
  4. Prostate cancer. National Comprehensive Cancer Network. https://www.nccn.org/guidelines/guidelines-detail?category=1&id=1459. Accessed Nov. 3, 2024.
  5. Choline C 11 Injection (approval letter). New Drug Application 203155. U.S. Food and Drug Administration. https://www.accessdata.fda.gov/scripts/cder/daf/index.cfm?event=overview.process&ApplNo=203155. Accessed Dec. 4, 2024.
  6. Evans JD, et al. Prostate cancer-specific PET radiotracers: A review on the clinical utility in recurrent disease. Practical Radiation Oncology. 2018; doi:10.1016/j.prro.2017.07.011.
  7. Murphy RC, et al. The utility of 11C-choline PET/CT for imaging prostate cancer: A pictorial guide. American Journal of Roentgenology. 2011; doi:10.2214/AJR.10.5491.
  8. Parvinian A, et al. 11C-choline PET/CT for detection and localization of parathyroid adenomas. American Journal of Roentgenology. 2018; doi:10.2214/AJR.17.18312.
  9. Primary hyperparathyroidism. National Institute of Diabetes and Digestive and Kidney Diseases. https://www.niddk.nih.gov/health-information/endocrine-diseases/primary-hyperparathyroidism. Accessed Dec. 20, 2024.

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Choline C-11 PET scan