Awake brain surgery

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Departments and specialties

Mayo Clinic has one of the largest and most experienced practices in the United States, with campuses in Arizona, Florida and Minnesota. Staff skilled in dozens of specialties work together to ensure quality care and successful recovery.

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Research

Mayo Clinic is constantly involved in innovation and medical research, finding solutions to improve your care and quality of life. Your doctor or someone on your medical team is likely involved in research related to your condition.

Mayo Clinic researchers study different types of neurosurgery, imaging and surgical techniques for awake brain surgery. Learn more about neurosurgery research.

Publications

See a list of publications about awake brain surgery by Mayo Clinic doctors on PubMed, a service of the National Library of Medicine.

Research Profiles

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By Mayo Clinic Staff

Awake brain surgery care at Mayo Clinic

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AboutCare at Mayo Clinic
May 08, 2026
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  1. Adult brain tumors treatment (PDQ) — Professional version. National Cancer Institute. https://www.cancer.gov/types/brain/hp/adult-brain-treatment-pdq. Accessed May 4, 2026.
  2. Brain tumor treatments and side effects. American Brain Tumor Association. https://www.abta.org/brain-tumor-treatment/treatments/surgery.html. Accessed March 23, 2026.
  3. Brain mapping. Epilepsy Foundation. https://www.epilepsy.com/learn/treating-seizures-and-epilepsy/surgery/pre-surgery-tests/brain-mapping. Accessed March 23, 2026.
  4. Health Education & Content Services. MC0714-02: Surgical treatment for epilepsy. Mayo Clinic; 2004.
  5. Surgery for brain tumors in adults. American Cancer Society. https://www.cancer.org/cancer/braincnstumorsinadults/detailedguide/brain-and-spinal-cord-tumors-in-adults-treating-surgery. Accessed March 23, 2026.
  6. Medical review (expert opinion). Mayo Clinic. April 20, 2026.
  7. Health Education & Content Services. MC1965: Craniotomy. Mayo Clinic; 2005.
  8. Aghajanian S, et al. Efficacy and safety of anesthetic agents in awake craniotomy using monitored anesthesia care protocol: A systematic review and meta-analysis. Neurosurgical Review. 2025; doi:10.1007/s10143-025-03176-y.

Related

Mayo Clinic in Rochester, Minnesota, Mayo Clinic in Phoenix/Scottsdale, Arizona, and Mayo Clinic in Jacksonville, Florida, have been ranked among the best Neurology & Neurosurgery hospitals in the nation by U.S. News & World Report.

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Awake brain surgery