Autologous stem cell transplant

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Why it's done

Most often, people who have autologous stem cell transplants have had high doses of chemotherapy and radiation to cure their conditions. These treatments can damage the bone marrow. An autologous stem cell transplant (ASCT) helps to restore the bone marrow by replacing damaged cells.

An autologous stem cell transplant can be used to treat more than 75 blood cancers and conditions. They include:

  • Hodgkin lymphoma.
  • Leukemia.
  • Multiple myeloma.
  • Non-Hodgkin lymphoma.
  • Plasma cell disorders.
  • Sickle cell disease.

ASCT also treats some conditions in which the immune system attacks its own body, such as multiple sclerosis, Crohn's disease and lupus.

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Doctors & Departments
Aug. 19, 2026
Print
  1. Blood and marrow stem cell transplantation guide. Blood Cancer United. https://bloodcancerunited.org/resources/educational-resources/publications. Accessed May 7, 2026.
  2. Holmberg LA, et al. Determining eligibility for autologous hematopoietic cell transplantation. https://www.uptodate.come/contents/search. Accessed May 7, 2026.
  3. Blood cancer and diseases treated by transplants. National Marrow Donor Program. https://bethematch.org/transplant-basics/how-transplants-work/diseases-treatable-by-transplants. Accessed May 7, 2026.
  4. Stem cell therapy for MS. National Multiple Sclerosis Society. https://www.nationalmssociety.org/managing-ms/treating-ms/treatments-and-medications/ahsct. Accessed May 7, 2026.
  5. Types of stem cell or bone marrow transplant. American Cancer Society. https://www.cancer.org/cancer/managing-cancer/treatment-types/stem-cell-transplant/types-of-transplants.html. Accessed May 11, 2026.

Autologous stem cell transplant

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