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1. A Study to Evaluate Setmelanoitide to Treat Patients with Rare Genetic Disorders of Obesity - Mayo Clinic

   The purpose of this study is to explore the impact of Setmelanotide on obesity in patients with various specific rare genetic mutations. Participation ...

2. Patents - Artificial Liver and Liver Transplantation: Scott L. Nyberg - Mayo Clinic Research

   Investigator, Patent title, Patent number, Patent date. Scott L. Nyberg, Fenestrated Funnel Bioartificial Liver, N/A, Patent pending (U.S. and international).

3. A Study Using the New TLR8 Agonist VTX-2337 and Cyclophosphamide in Treating Patients with Metastatic, Persistent, Recurrent, or Progressive Solid Tumors - Mayo Clinic

   About this study. This phase Ib trial studies the best way of TLR8 Agonist VTX-2337 and cyclophosphamide in treating patients with a solid tumor that has ...

4. Breast cancer - Doctors and departments - Mayo Clinic

   Learn about this common cancer, including information on prevention, symptoms, diagnosis and treatment.

5. A Randomized Phase 3 Trial of TRC105 and Pazopanib Versus Pazopanib Alone in Patients with Advanced Angiosarcoma (TAPPAS) - Mayo Clinic

   About this study. This is a study of TRC105 in combination with standard dose pazopanib compared to single agent pazopanib in patients with angiosarcoma not ...

6. A Single Patient Treatment Use of UX007 for Adult Malonyl-coA Decarboxylase Deficiency - Mayo Clinic

   Participant eligibility includes age, gender, type and stage of disease, and previous treatments or health concerns. Guidelines differ from study to study, and ...

7. Efficacy of Daromun Neoadjuvant Intratumoral Treatment in Clinical Stage IIIB/C Melanoma Patients

   The purpose of this study is to demonstrate that a neoadjuvant Daromun treatment followed by surgery and adjuvant therapy improves in a statistically ...

8. A First-in-Human (FIH) Study to Evaluate the Safety and Tolerability of VVD-130037 in Participants With Advanced Solid Tumors - Mayo Clinic

   The purpose of this FIH study to evaluate the safety, pharmacokinetics, pharmacodynamics, and preliminary efficacy of VVD-130037 in participants with advanced ...

9. A Study to Establish a Vascular Anomalies Tissue Repository - Mayo Clinic

   About this study. The purpose of this study is to develop a resource (bank) of biospecimens and data collected from individuals with a vascular tumor or ...

10. NEURO-TTRansform: A Study to Evaluate the Efficacy and Safety of AKCEA-TTR-LRx in Participants With Hereditary Transthyretin-Mediated Amyloid Polyneuropathy - Mayo Clinic

    Neuropathy Symptom and Change Score (NSC); Physical component summary (PCS) score of 36-Item Short Form Survey (SF-36); Polyneuropathy disability (PND) score ...