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  1. A Study Using the New TLR8 Agonist VTX-2337 and Cyclophosphamide in Treating Patients with Metastatic, Persistent, Recurrent, or Progressive Solid Tumors - Mayo Clinic

    About this study. This phase Ib trial studies the best way of TLR8 Agonist VTX-2337 and cyclophosphamide in treating patients with a solid tumor that has ...

  2. A Randomized Phase 3 Trial of TRC105 and Pazopanib Versus Pazopanib Alone in Patients with Advanced Angiosarcoma (TAPPAS) - Mayo Clinic

    About this study. This is a study of TRC105 in combination with standard dose pazopanib compared to single agent pazopanib in patients with angiosarcoma not ...

  3. A Single Patient Treatment Use of UX007 for Adult Malonyl-coA Decarboxylase Deficiency - Mayo Clinic

    Participant eligibility includes age, gender, type and stage of disease, and previous treatments or health concerns. Guidelines differ from study to study, and ...

  4. Efficacy of Daromun Neoadjuvant Intratumoral Treatment in Clinical Stage IIIB/C Melanoma Patients

    The purpose of this study is to demonstrate that a neoadjuvant Daromun treatment followed by surgery and adjuvant therapy improves in a statistically ...

  5. A Study to Establish a Vascular Anomalies Tissue Repository - Mayo Clinic

    About this study. The purpose of this study is to develop a resource (bank) of biospecimens and data collected from individuals with a vascular tumor or ...

  6. A Study Using Avelumab in Non-Small Cell Lung Cancer that has Progressed - Mayo Clinic

    The purpose of this study is to demonstrate avelumab's overall survival superiority versus docetaxel in patients with programmed death ligand 1 (PD-L1) positive ...

  7. Novel Support Options in Autologous Stem Cell Transplant for Multiple Myeloma - Mayo Clinic

    About this study. Does Tai Chi Easy (TCEasy), a simple and repetitive form of exercise that consists of movements with meditation, improve quality of life ...

  8. A Study of CG-806 in Patients with Relapsed or Refractory CLL/SLL or Non-Hodgkin's Lymphomas - Mayo Clinic

    Participant eligibility includes age, gender, type and stage of disease, and previous treatments or health concerns. Guidelines differ from study to study, and ...

  9. A Study to Test How Effective and Safe GLPG1690 is for Subjects With Idiopathic Pulmonary Fibrosis (IPF) When Used Together With Standard Medical Treatment - Mayo Clinic

    The primary purpose of this study is to see how GLPG1690 works together with current standard treatment on lung function and IPF disease in general. The study ...

  10. A Study of APL-2 Therapy in Patients with Geographic Atrophy Associated with Age-Related Macular Degeneration - Mayo Clinic

    The primary objectives of the study are to assess the safety, tolerability and evidence of activity of multiple intravitreal (IVT) injections of APL-2 in ...