Search Results 41-50 of 9664 for TNF

1. Ulcerative Colitis Clinical Trials - Mayo Clinic Research

   ... Tumor Necrosis Factor (TNF) Inhibitors Rochester, MN. This phase III, double blind, placebo-controlled, multicenter study will investigate the efficacy and ...

2. Oncolytic Adenovirus Coding for TNFa and IL2 (TILT-123) With Pembrolizumab or Pembrolizumab and Pegylated Liposomal Doxorubicin as Treatment for Ovarian Cancer. (PROTA) - Mayo Clinic

   ... tumor necrosis factor alpha (TNFa) and interleukin-2 (IL-2). These cytokines result in immunological danger signaling and multiple appealing T-cell effects ...

3. Investigating autoinflammatory epileptic encephalopathies in children - Mayo Clinic

   In addition to analyzing patient samples, we are using animal models to study the cytokines associated with seizures. That work focuses primarily on TNF because ...

4. Mayo Clinic Researchers Find New Molecule to Target in Pancreatic Cancer Treatment

   The research team discovered that increased activity of the alternative NF-kB pathway results from suppression of TNF receptor-associated factor 2, or TRAF2.

5. Publications - Brett A. Koplin, M.D. - Mayo Clinic

   Cachectin/tumor necrosis factor-secreting tumor in skeletal muscle induces chronic cachexia, while implantation in brain induces predominantly acute anorexia. J ...

6. Crohn's Disease Clinical Trials - Mayo Clinic Research

   ... tumor necrosis factor (TNF-IR). Participants who enroll on the basis of refractory or intolerance to CS and/or IS may have been previously exposed to anti ...

7. Inflammatory bowel disease biobank research update - Mayo Clinic

   ... tumor necrosis factor (TNF) therapy. They examined how a patient's genetic risk burden or profile affects the disease course and individual responses to ...

8. A Study to Establish An Integrated Biomarker Panel for COVID-19 Infection Risk and Severity Prediction - Mayo Clinic

   Hypothesis: Baseline cytokine (IL-1β, IL-6, IL-4, IL-10, IFN-g and TNF-a) and the immune cellular repertoire (helper/CD4+, cytotoxic/CD8+, T-regulatory ...

9. Citrullinated Antigens in Rheumatoid Arthritis Patient-Matched Synovial Biopsy, Synovial Fluid, and Serum Samples - Mayo Clinic

   ... TNF-inhibitors. Correlate local levels of antigen with systemic levels measured in serum using matched patient tissue and blood sample, and correlate local ...

10. A Study to Evaluate the Effectiveness and Safety of Triple Combination Therapy in High Risk Crohn's Disease (CD) - Mayo Clinic

    ... tumor necrosis factor (TNF) antagonist (adalimumab subcutaneously [SC]), and an immunomodulator (oral methotrexate) on endoscopic remission in participants ...