Search Results 481-490 of 17301 for egfr

1. Rovalpituzumab Tesirine in Delta-Like Protein 3-Expressing Advanced Solid Tumors - Mayo Clinic

   5× ULN or estimated glomerular filtration rate (eGFR) ≥0 mL/min/1.73m2. Serum albumin ≥3.0 g/dL. Last dose of any prior therapy administered by the ...

2. Safety, Efficacy And Tolerability Of Ianalumab Versus Placebo, Combination With SoC Therapy, In Participants With Active Lupus Nephritis - Mayo Clinic

   - eGFR ≥ 25mL/min/1.73 m^2. Participants must be currently on, or willing to initiate SoC induction therapy for LN according to the institutional practices ...

3. A Phase 1/2 Trial Of TER-2013 In Patients With Solid Tumors Harboring AKT/PI3K/PTEN Pathway Alterations - Mayo Clinic

   * Known EGFR, KRAS, NRAS, HRAS, or BRAF oncogenic-driver co-mutation with PI3K/AKT/PTEN alteration * Clinically significant abnormalities of glucose metabolism

4. Focal segmental glomerulosclerosis (FSGS) - Doctors and departments - Mayo Clinic

   Departments and specialties. Mayo Clinic has one of the largest and most experienced practices in the United States, with campuses in Arizona, ...

5. A Study Testing The Combination Of Dasatinib Or Imatinib To Chemotherapy Treatment With Blinatumomab For Children, Adolescents, And Young Adults With Philadelphia Chromosome Positive (Ph+) Or ABL-Class Philadelphia Chromosome-Like (Ph-Like) B-cell Acute Lymphoblastic Leukemia (B-ALL) - Mayo Clinic

   * Estimated GFR (eGFR) ≥ 50 mL/min/1.73 m2 * Measured GFR ≥ 50 mL/min/1.73 m\^2 (any age). If measured GFR is used, it must be performed using direct ...

6. A Study to Evaluate Ischemia in Women to Reduce Non-obstructive CAD Events - Mayo Clinic

   End-stage renal disease, on dialysis, or estimated glomerular filtration rate (eGFR) < 30 ml/min. Severe valvular disease or likely to require surgery/TVAR ...

7. Randomized, Open Label, Clinical Study Of The Targeted Therapy, Palbociclib, To Treat Metastatic Breast Cancer

   This relieves feedback inhibition of upstream EGFR family kinases, resensitizing tumors to EGFR/HER2 blockade. Consequently, dual inhibition of EGFR/HER2 ...

8. Cetuximab With Or Without Tivantinib In Treating Patients With Head And Neck Cancer That Is Recurrent, Metastatic, Or Cannot Be Removed By Surgery - Mayo Clinic

   Patients who have received treatment with an EGFR or MET inhibitor in the palliative treatment setting are ineligible; Patients with known, active brain ...

9. A Study to Evaluate the Effectiveness and Safety of G10 in Subjects with Transthyretin Amyloid Cardiomyopathy - Mayo Clinic

   Has estimated glomerular filtration rate (eGFR) by MDRD formula < 15 mL/min/1.73 m^2 at Screening. Known hypersensitivity to study drug (AG10 or placebo) ...

10. Evaluation Of The GORE® Ascending Stent Graft - Mayo Clinic

    Renal failure, defined as patients with an estimated Glomerular Filtration Rate (eGFR) < 30 (mL/min/1.73 m^2) or currently requiring dialysis. Life ...