Search Results 471-480 of 17205 for egfr

  1. Laryngeal (Voice Box) Cancer Clinical Trials - Mayo Clinic Research

    The purpose of this study is to demonstrate the safety and tolerability of JAB-3312 in combination with anti-PD-1 mAb or MEKi or KRASi or EGFR-TKI in patients ...

  2. CLIP-IT Post Market Study: Exclusion of the Left Atrial Appendage With Penditure™ - Mayo Clinic

    * Chronic Kidney Disease Stage IV or V (eGFR \<30 ml/min) * NYHA Class IV heart failure symptoms * Patient has a documented history of substance (drug or ...

  3. A Study of Gemcitabine-Cisplatin Chemotherapy plus Necitumumab in the First-Line Treatment of Patients with Lung Cancer - Mayo Clinic

    ... (EGFR), vascular endothelial growth factor (VEGF), or VEGF receptor; Previous chemotherapy for NSCLC; Major surgery or received any investigational therapy in ...

  4. An Extension Study to Evaluate Long-term Safety of Sacubitril/Valsartan in Pediatric Patients With Heart Failure (HF) - Mayo Clinic

    - Significant renal estimated glomerular filtration rate disorder (eGFR calculated using modified Schwartz formula <30% mean GFR for age); hepatic disorder ...

  5. Nephrology and Hypertension - Clinical trials

    The natural course of autosomal dominant polycystic kidney disease (ADPKD) is highly variable and typically characterized by progressive enlargement of cysts ...

  6. A Study Assessing HMB-002 In Participants With Von Willebrand Disease - Mayo Clinic

    Participation eligibility · Renal: Estimated glomerular filtration rate (eGFR) of ≥45 ml/min/1.73m^2. · Hepatic: Aspartate aminotransferase (AST), alanine ...

  7. A Study of Daratumumab in Patients With Relapsed or Refractory Waldenström Macroglobulinemia - Mayo Clinic

    EGFR ≥ 30 ml/min;; Not on any active therapy for other malignancies with the exception of topical therapies for basal cell or squamous cell cancers of the ...

  8. A Study To Assess Efficacy And Safety Of Pembrolizumab With Or Without Sacituzumab Tirumotecan (MK- 2870) In Adult Participants With Resectable Non Small Cell Lung Cancer (NSCLC) Not Achieving Pathological Complete Response (pCR) (MK-2870-019) - Mayo Clinic

    * Has confirmation that either epidermal growth factor receptor (EGFR)-directed or anaplastic lymphoma kinase (ALK)-directed therapy is not indicated as ...

  9. Dapagliflozin in Type 2 Diabetes or Pre-diabetes, and PRESERVED Ejection Fraction Heart Failure - Mayo Clinic

    Estimated glomerular filtration rate (eGFR) < 30 at the screening visit; Admission for an acute coronary syndrome (ST-elevation MI, non-ST-elevation MI, or ...

  10. Pembrolizumab Plus Epacadostat Alone or With Platinum-based Chemotherapy Versus Pembrolizumab Plus Platinum-based Chemotherapy Plus Placebo in Metastatic Non-Small Cell Lung Cancer (KEYNOTE-715-02/ECHO-306) - Mayo Clinic

    Histologically or cytologically confirmed diagnosis of stage IV NSCLC without epidermal growth factor receptor (EGFR)-sensitizing mutation, ROS1 and/or ...