Search Results 291-300 of 17301 for egfr

  1. To Evaluate The Long-term Safety And Tolerability Of Acoramidis In Participants With Newly Diagnosed ATTR-CM (ACT-EARLY OLE) - Mayo Clinic

    Stage IV or V chronic kidney disease (corresponding to an eGFR ≤ 29 mL/min/1.73 m2), or undergoing renal dialysis, or recipient of a kidney transplant. 5 ...

  2. Study of Hemodynamic-GUIDEd Management of Heart Failure - Mayo Clinic

    Glomerular Filtration Rate (eGFR) < 25 mL/min and non-responsive to diuretic therapy, or receiving chronic dialysis. Inability to tolerate or receive dual ...

  3. A Study of BBI608 Administered With Paclitaxel in Adult Patients With Advanced Malignancies - Mayo Clinic

    EGFR-positive or ALK-positive patients must have received at least one line of EGFR-directed or ALK-directed therapy, respectively; d. Must have received ...

  4. Impact of CardiolRxTM on Recurrent Pericarditis - Mayo Clinic

    Estimated glomerular filtration rate (eGFR) <30 mL/min at screening 3. Elevated alanine aminotransferase (ALT) or aspartate aminotransferase (AST) > 5 times

  5. A Study To Assess An Intact Parathyroid Hormone Assay Under Development By Ortho Clinical Diagnostics

    eGFR of less than 20 mL/min/1.73 m2 (can be from Standard of Care result). Clinical diagnosis of Secondary Hyperparathyroidism. Able to provide a minimum of ...

  6. Safety, Tolerability, And Pharmacodynamics Of NOV-001 In Adult Subjects - Mayo Clinic

    Estimated glomerular filtration rate (eGFR) < 80 mL/min/1.73 m^2 at Screening. Oral or parenteral antibiotics within 4 weeks prior to Screening, or ...

  7. Colchicine to Prevent Post-Pericardiotomy Syndrome and Atrial Fibrillation - Mayo Clinic

    eGFR < 30 mL/min/1.73 m2, serum creatinine > 2.5 mg/dL or requiring dialysis; Known permanent or current atrial fibrillation (history of paroxysmal atrial ...

  8. A Study To Evaluate The Safety, Tolerability, And Effectiveness Of Cilofexor In Non-Cirrhotic Adults With Primary Sclerosing Cholangitis - Mayo Clinic

    Estimated glomerular filtration rate (eGFR) ≥ 30 milliliter/minute (mL/min), as calculated by the Cockcroft-Gault equation;; ALT ≤ 8 x upper limit of the ...

  9. Study of LNP023 (iptacopan) in patients with ANCA-associated vasculitis - Mayo Clinic

    Severe kidney disease defined as estimated glomerular filtration rate (eGFR) <15 mL/minute/1.73m2, or kidney failure defined as receiving renal replacement ...

  10. Study of Pembrolizumab (MK-3475) Compared to Platinum-Based Chemotherapies in Participants With Metastatic Non-Small Cell Lung Cancer (MK-3475-024/KEYNOTE-024) - Mayo Clinic

    EGFR sensitizing mutation and/or ALK translocation; Currently participating or has participated in a study of an investigational agent or using an ...