Search Results 271-280 of 17158 for egfr

1. A Study of Neoadjuvant Atezolizumab Plus Chemotherapy Versus Placebo Plus Chemotherapy in Patients With Resectable Stage II, IIIA, or Select IIIB Non-Small Cell Lung Cancer (IMpower030) - Mayo Clinic

   Patients with non-squamous NSCLC histology that have unknown EGFR and/or ALK status require test results at screening. ALK and/or EGFR may be assessed ...

2. Efficacy and Safety of Lixivaptan in the Treatment of Autosomal Dominant Polycystic Kidney Disease - Mayo Clinic

   - eGFR ≥25 mL/min/1.73 m2 and ≤90 mL/min/1.73 m2 - Body mass index (BMI) between 18 and 40 kg/m2 - Control of hypertension consistent with KDIGO ...

3. Pilot Study to Evaluate the Safety and Efficacy of Abatacept in Adults and Children 6 Years and Older With Excessive Loss of Protein in the Urine Due to Either Focal Segmental Glomerulosclerosis (FSGS) or Minimal Change Disease (MCD) - Mayo Clinic

   eGFR ≥ 45 for children and adults; Concomitant use of angiotensin-converting-enzyme inhibitor (ACEi) or angiotensin receptor blocker (ARB) at stable doses ...

4. Investigation of the Safety and Pharmacology of Dry Powder Inhalation of Treprostinil - Mayo Clinic

   The patient has severe renal impairment (eGFR < 30). Additional Exclusion Criteria for PK Sub-Study. The patient meets any of Primary Exclusion Criteria #1 ...

5. A Study of Encorafenib Plus Cetuximab Taken Together With Pembrolizumab Compared to Pembrolizumab Alone in People With Previously Untreated Metastatic Colorectal Cancer - Mayo Clinic

   ... (EGFR) inhibitor (eg, cetuximab, panitumumab). - Previous treatment with an immune checkpoint inhibitor (eg, anti-programmed cell death [PD-1], anti-PD-L1 or ...

6. A Study to Assess the Effect of Dexpramipexole in Adolescents and Adults With Severe Eosinophilic Asthma (EXHALE-3) - Mayo Clinic

   using the Bedside Schwartz [Schwartz and Work, 2009] eGFR formula for age <18). 21. Active liver disease defined as any known current infectious, neoplastic ...

7. A Study To Assess Efficacy And Safety Of Baxdrostat In Participants With Primary Aldosteronism - Mayo Clinic

   * eGFR ≥ 45 mL/min/1.73m2 at Screening * Serum potassium level ≥ 3.0 and \< 5.0 mmol/L at Screeningdetermined as per the central laboratory. * Have a ...

8. A Study of Sotatercept for the Treatment of Pulmonary Arterial Hypertension (STELLAR) - Mayo Clinic

   Estimated glomerular filtration rate (eGFR) < 30 mL/min/m^2 (as defined by the Modification of Diet in Renal Disease [MDRD] equation);; Serum alanine ...

9. EntrestoTM (LCZ696) In Advanced Heart Failure (LIFE Study) - Mayo Clinic

   Estimated glomerular filtration rate (eGFR) < 20 mL/min/1.73 m2 at baseline. Co-morbid conditions that may interfere with completing the study protocol ...

10. Laryngeal Clinical Trials - Mayo Clinic Research

    The purpose of this study is to demonstrate the safety and tolerability of JAB-3312 in combination with anti-PD-1 mAb or MEKi or KRASi or EGFR-TKI in patients ...