Search Results 21-30 of 17042 for Somatic

  1. Telomere Biology Disorders - Center for Individualized Medicine - Mayo Clinic Research

    ... somatic mutations, which happen randomly and are not passed down. Doctors and researchers at Mayo Clinic have extensive experience evaluating and treating ...

  2. A Study of Rucaparib in Patients With Pancreatic Cancer and a Known Deleterious BRCA Mutation - Mayo Clinic

    Documented deleterious or suspected deleterious (or equivalent interpretation) BRCA mutation (germline or somatic) as assessed by a local laboratory ...

  3. An Open-label, Phase 2 Basket Study of Neratinib in Patients with Solid Tumors with Somatic Activating HER Mutations - Mayo Clinic

    An Open-label, Phase 2 Basket Study of Neratinib in Patients with Solid Tumors with Somatic Activating HER Mutations · More about research at Mayo Clinic · Mayo ...

  4. VEXAS syndrome - Symptoms and causes - Mayo Clinic

    Somatic means that the changed gene happens after birth and doesn't pass through families. Treatment most often involves medicines. Sometimes it involves ...

  5. A Study to Evaluate Binimetinib in Combination with Encorafenib in Patients with Pancreatic Malignancies and a Somatic BRAFV600E Mutation - Mayo Clinic

    Giving binimetinib and encorafenib may work better compared to the usual treatment in treating patients with pancreatic cancer and a somatic BRAF V600E mutation ...

  6. Alexej Abyzov, Ph.D. - Mayo Clinic Faculty Profiles

    Somatic variations and single cell genomics; Cancer genomics. Significance to patient care. The ability to discover and predict the effects of (interpret) ...

  7. Stem cells: What they are and what they do - Mayo Clinic

    Therapeutic cloning, also called somatic cell nuclear transfer, is a way to create versatile stem cells independent of fertilized eggs. In this technique ...

  8. Genomic Methods - Translational Neuro-Oncology: Jann N. Sarkaria - Mayo Clinic Research

    Read more about genomic methods using RNA sequencing and whole-exome sequencing and about identification of somatic alternations in samples from the Mayo ...

  9. Zhifu Sun, M.D. - Mayo Clinic Faculty Profiles

    Unlike somatic mutations with a low recurrence frequency in most cancers, DNA methylation changes occur more universally. These cancer hallmarks can be ...

  10. Human developmental disorders arising from mutations in epigenetic regulator genes - Research

    Disruption of epigenetic regulator genes in cancer is common. This disruption typically manifests as the loss of both gene copies in somatic cells. But single ...