Search Results 1281-1290 of 16384 for alt

1. A Phase 1 Study Evaluating the Safety, PK, and Clinical Effects of PT-112 in Subjects With Advanced Solid Tumors

   ALT and AST ≤ 2.5 x upper limit of normal (ULN) (≤ 5.0 x ULN if liver metastases are present);; Serum bilirubin V 1.5 x ULN (≤ 3.0 x ULN if liver ...

2. Safety Study of Nivolumab With Nab-Paclitaxel Plus or Minus Gemcitabine in Pancreatic Cancer, Nab-Paclitaxel / Carboplatin in Stage IIIB/IV Non-Small Cell Lung Cancer or Nab-Paclitaxel in Recurrent Metastatic Breast Cancer - Mayo Clinic

   Aspartate Aminotransferase (AST) and Alanine Aminotransferase (ALT) ≤ 2.5 x Upper Limit of Normal (ULN) or ≤ 3.0 x ULN if liver tumor is present,; Serum ...

3. A Study of the Effects of Decreasing the Lasix Dose on the Cardiorenal System - Mayo Clinic

   Alanine Aminotransferase (ALT) result >1.5 times the upper limit of normal; Serum sodium of < 125 milliequivalent (mEq)/dL or > 150 mEq/dL; Serum potassium of ...

4. Nilotinib and Combination Chemotherapy in Treating Patients with Newly Diagnosed Philadelphia Chromosome-Positive Acute Lymphoblastic Leukemia or Blastic Phase Chronic Myelogenous Leukemia - Mayo Clinic

   Serum glutamic pyruvic transaminase (SGPT) (alanine aminotransferase [ALT]) ≤ 3 x ULN; Creatinine ≤ 1.5 x ULN; Negative serum pregnancy test done ≤ 7 days ...

5. Alisertib and Fulvestrant in Treating Patients With Hormone Receptor Positive Breast Cancer That is Metastatic or Locally Advanced and Cannot Be Removed by Surgery - Mayo Clinic

   Absolute neutrophil count (ANC) ≥ 1500/mm^3; Platelet (PLT) ≥ 100,000/mm^3; Total bilirubin ≤ 1.5 upper limit of normal (ULN); Alanine transaminase (ALT) ...

6. A Phase II Study of ABC294640 as Second-Line Monotherapy in Patients With Advanced Hepatocellular Carcinoma - Mayo Clinic

   AST (SGOT), ALT (SGPT) 3 x ULN (CTCAE Grade 1 baseline). Acceptable kidney function: Serum creatinine ≤ 1.5 XULN (CTCAE Grade 1 baseline). Acceptable ...

7. A Trial to Evaluate the Efficacy and Safety of MOR208 With Bendamustine (BEN) Versus Rituximab (RTX) With BEN in Adult Patients With Relapsed or Refractory Diffuse Large B-cell Lymphoma (DLBCL) - Mayo Clinic

   ALT, AST and AP ≤3 × ULN or <5 × ULN in cases of documented liver involvement by lymphoma; Serum creatinine ≤2.0 x ULN or creatinine clearance must be ≥40 ...

8. A Study of BBI608 in Combination With Standard Chemotherapies in Adult Patients With Advanced Gastrointestinal Cancer - Mayo Clinic

   AST level ≤2.5 x ULN and ALT ≤ 2.5 × ULN. For patients with liver metastases, AST ≤3.5 x ULN, and AST ≤3.5 x ULN may be enrolled if agreed upon by the ...

9. Comparison of Anti-coagulation and Anti-Platelet Therapies for Intracranial Vascular Atherostenosis - Mayo Clinic

   ... ALT > 3 x normal, cirrhosis), or CrCl < 15 mL/min or on dialysis. - Major surgery (including open femoral, aortic, or carotid surgery, cardiac) within ...

10. A Study of Tucatinib Plus Trastuzumab Deruxtecan in HER2+ Breast Cancer - Mayo Clinic

    ... (ALT) are eligible b. Transaminases (AST and ALT) ≤ 3 x ULN (≤ 5 x ULN if liver metastases are present). Have adequate baseline hematologic parameters as ...