Search Results 1261-1270 of 16399 for alt

  1. Combination Chemotherapy in Treating Younger Patients with Newly Diagnosed, Non-Metastatic Desmoplastic Medulloblastoma - Mayo Clinic

    ... [ALT]) < 2.5 x upper limit of normal (ULN) for age; Central nervous system function defined as: Patients with seizure disorder may be enrolled if on ...

  2. PRE-I-SPY Phase I/Ib Oncology Platform Program - Mayo Clinic

    - Aspartate aminotransferase (AST) and alanine aminotransferase (ALT) ≤ 3.0 x ULN - Estimated Creatinine clearance (using Cockcroft-Gault formula) ≥ 60 mL ...

  3. A Dose Ranging Phase IIa Study Of 6 Hour Intravenous Dosages Of CXL-1427 In Patients Hospitalized With Heart Failure - Mayo Clinic

    Have an ALT or AST >3 times the upper normal limit or a hemoglobin <10g/dl (100g/L) within 8 hours before initiation of the study drug infusion;; Have a ...

  4. Study of Nanoliposomal Irinotecan (Nal-IRI)-Containing Regimens in Patients With Previously Untreated, Metastatic Pancreatic Adenocarcinoma - Mayo Clinic

    AST and ALT ≤ 2.5 x ULN (≤ 5 x ULN is acceptable if liver metastases are present). Adequate renal function as evidenced by serum creatinine ≤ 1.5 x ULN ...

  5. Perioperative Therapy for Resectable and Borderline-Resectable Pancreatic Adenocarcinoma With Molecular Correlates - Mayo Clinic

    Patients must have adequate liver function: - aspartate aminotransferase (AST) and Alanine Aminotransferase (ALT) < 2.5 X upper limit of normal - Alkaline ...

  6. A Study of Napabucasin (BBI-608) in Combination With FOLFIRI in Adult Patients With Previously Treated Metastatic Colorectal Cancer - Mayo Clinic

    Must have alanine transaminase (ALT) ≤ 3 × institutional upper limit of normal (ULN) [≤ 5 × ULN in presence of liver metastases] within 14 days prior to ...

  7. A Study to Evaluate Ipilimumab Administered Intra-lymphatically Using the Sofusa® DoseConnect™ DEVICE with IV-administered Nivolumab in Patients with Metastatic Melanoma - Mayo Clinic

    Alanine aminotransferase (ALT) and aspartate transaminase (AST) ≤ 3.0 × ULN;; Serum creatinine ≤ 2.0 × ULN;; Calculated creatinine clearance ≥ 40 ml/min ...

  8. A Study to Evaluate AVID200 in Myelofibrosis Patients - Mayo Clinic

    ALT (SGPT) and/or AST (SGOT) ≤ 3 x upper limit of normal (ULN), or ≤ 4 x ULN (if upon judgment of the treating physician, it is believed to be due to ...

  9. Radiation Therapy and Cisplatin With or Without Surgery in Treating Patients With Stage III-IV Oropharyngeal Cancer - Mayo Clinic

    Aspartate aminotransferase (AST) or alanine aminotransferase (ALT) < 3 x the upper limit of normal; Serum creatinine ≤ 1.5 mg/dl and/or creatinine clearance ...

  10. MK-8228 (Letermovir) PK In Pediatric Kidney Transplant Recipients - Mayo Clinic

    Has serum AST or ALT >5 x the ULN or serum total bilirubin >2.5 x ULN within 14 days before enrollment. Note: Participants who meet this exclusion criterion ...