Search Results 461-470 of 38031 for Two-phase

  1. Hematology - Clinical trials

    In Part 2, the step-up dose identified in Part 1 will be used followed by ... This phase 1b trial is an open-label study designed to assess the safety ...

  2. Non-Hodgkin Lymphoma Clinical Trials - Mayo Clinic Research

    This is a phase 3, randomized, 2-arm, open-label, international trial evaluating alisertib compared with single-agent treatment, as selected by the investigator ...

  3. End-stage renal disease - Diagnosis and treatment - Mayo Clinic

    Stage 1, 90 or above, Healthy kidney function. Stage 2, 60 to 89, Mild loss of kidney function. Stage 3a, 45 to 59, Mild to moderate loss of kidney function.

  4. SGI-110 in Patients with Myelodysplastic Syndromes (MDS) or Acute Myelogenous Leukemia (AML) - Mayo Clinic

    Phase 1-2 dose escalation randomized study in patients with intermediate or high risk myelodysplastic syndromes (MDS) or acute myelogenous leukemia (AML).

  5. Intrathecally Administered Gene Therapy APB-102 In Rapidly Progressive ALS Patients With SOD1 Mutations - Mayo Clinic

    This is a Phase 1/2 open-label, multicenter study to evaluate the safety and tolerability and to explore the efficacy of gene therapy AMT-162 in ...

  6. Alzheimer's treatments: What's on the horizon? - Mayo Clinic

    These therapies may reduce the amount of beta-amyloid formed in the brain. Research has shown that beta-amyloid is produced from a "parent protein" in two steps ...

  7. Chronic Lymphocytic Leukemia Clinical Trials - Mayo Clinic Research

    Phase 2 (stage 1): To evaluate the activity of single-agent Isatuximab at different doses/schedules and to select dose and regimen to further evaluate the ...

  8. Study of Two Doses of MK-3475 (Pembrolizumab) Versus Docetaxel in Previously-Treated Participants With Non-Small Cell Lung Cancer (MK-3475-010/KEYNOTE-010) - Mayo Clinic

    Participation eligibility. Participant eligibility includes age, gender, type and stage of disease, and previous treatments or health concerns. Guidelines ...

  9. Mayo Clinic Q and A: Facial drooping in children

    The gracilis muscle transfer is the favored approach to restore a symmetric, spontaneous smile and usually is performed in two stages. The first stage ...

  10. Colon Cancer Clinical Trials - Mayo Clinic Research

    The primary purpose of this study for Step 2: To assess the anti-tumour activity of MEN1611 in combination with cetuximab in patients with PIK3CA mutated ...