Traveling by bus or train to Mayo Clinic's campus in Minnesota

Traveling by bus

Jefferson Lines serves Rochester, Minnesota, with connecting service from locations throughout the United States. Call 800-451-5333 (toll-free) for tickets and more information.

Traveling by train

Amtrak offers daily passenger service between Chicago and Minneapolis/St. Paul. This service includes a scheduled stop in La Crosse, Wisconsin, where a connecting shuttle bus provides transportation to Rochester. When booking train tickets, be sure to book to Rochester. This will ensure that you have a connection between your final train stop and Rochester. Call Amtrak at 800-872-7245 (toll-free) for transportation information.

Mayo Clinic Concierge Services can assist you with questions related to lodging, transportation, local businesses and attractions.

For more details about traveling to Rochester, see the Rochester Convention & Visitors Bureau.