Orthopedic Surgery

Below are current clinical trials.

Filter this list of studies by location, status and more.

1. A Study to Evaluate the Safety and Feasibility of Intra-articular Transplantation of Autologous Adipose Derived Stromal Vascular Fraction (SVF) for Treatment of Osteoarthritis of the Knee

   Jacksonville, Fla.

   The purpose of this study is to determine the safety and feasibility of autologous, adipose derived stromal vascular fraction injections in the treatment of knee osteoarthritis.

2. Scoliosis Shared Decision Making

   Rochester, Minn.

   Analysis of video encounters between providers, patients, and families will be used to develop a shared decision making tool for patients deciding between surgery and observation for scoliosis treatment.

3. Minnesota Spinal Cord Injury Data Network

   Rochester, Minn.

   This is a study to generate feasibilty data regarding the collection of health and psychosocial outcomes after acquired spinal cord injury (SCI)

4. A Study to Investigate the Use of Diaphragm Muscle Ultrasound to Assess the Duration of a Diaphragm Nerve Block

   Rochester, Minn.

   The purpose of this study is to to determine the impact of anesthesia (liposomal bupivacaine) on diaphragm muscle forces using a non-invasive ultrasonographic shear wave elastography (SWE) method.  

5. A Study to Determine A Patient's Preference for Direct Anterior Approach Versus Posterior Approach in Primary Total Hip Arthroplasty

   Jacksonville, Fla.

   The purpose of this study is to collect the patient’s perspective on total hip arthroplasty (THA) approach in a single-surgeon, crossover cohort of patients who first underwent total hip arthroplasty using a posterior approach followed by a direct anterior (DA) THA.

6. Epidural and Dorsal Root Stimulation in Humans with Spinal Cord Injury

   Rochester, Minn.

   A study to compare electrophysiologic activity of epidural stimulation and dorsal root ganglion stimulation, as well as quantify changes in motor performance with both types of stimulation over the course of 10 rehabilitation sessions.

7. Study to Evaluate the Continued Safety and Probable Benefit of the MID-C System for 5 Years Post-Implantation in Adolescent Idiopathic Scoliosis (AIS)

   Rochester, Minn., Minneapolis, Minn.

   The purpose of this study is to evaluate the continued safety and probable benefit of the MID-C system for 5 years post-implantation in Adolescent Idiopathic Scoliosis (AIS).

8. Comparative Effectiveness of Pulmonary Embolism Prevention After Hip and Knee Replacement

   Rochester, Minn.

   PEPPER is a randomized study comparing the three most commonly used anticoagulants in North America in patients who have elected to undergo primary or revision hip or knee joint replacement surgery. The anticoagulants being compared are enteric coated aspirin, low intensity warfarin, and rivaroxaban.

9. A Study of the Baseball Swing Through Motion Capture

   Rochester, Minn.

   The primary aim of this study is to develop a deeper understanding of the kinetics and kinematics of the baseball swing.  Secondary aims include: describing the relative stress/forces across major lower extremity joints and spine during the baseball swing, assessing the intra- and inter-batter variability in the swing, determining how kinetics/kinematics vary across different batting scenarios, determining how kinetics/kinematics vary across different batting efforts, correlating swing kinetics with bat velocity, correlating swing kinetics with ball exit velocity, assessing the validity and reliability of various wearable devices compared to motion capture, determining the impact of bat weight on swing kinetics/kinematics, determining the impact of ball weight on swing kinetics/kinematics, assessment of eye tracking, and comparison of male baseball swing to female softball swing.

    

    

   Traditionally, batting mechanics have been analyzed qualitatively during direct observation or by viewing video tapes of batting motions.  More recently, sophisticated motion analysis systems have facilitated the collection of quantitative, three-dimensional kinematic information of the batting motion.  These advancements provide the opportunity for more detailed analyses of batting motions that can be integrated into the evaluation and treatment of baseball batters at the Mayo Clinic, with the hypothesis that metrics gathered from the force plates and motion capture are more reliable than the Motus wearables.

    

10. Does the Critical Shoulder Angle Influence the Rotator Cuff Failure After Anatomic Shoulder Arthroplasty?

    Rochester, Minn.

    The purpose of this study is to:

    • Evaluate the influence of the critical shoulder angle (CSA) on outcomes after total anatomic shoulder arthroplasty; and
    • Evaluate the influence of the critical shoulder angle (CSA) on rotator cuff failure after total anatomic shoulder arthroplasty.