Orthopedic Surgery

Below are current clinical trials.

64 studies in Orthopedic Surgery
(open studies only).

Filter this list of studies by location, status and more.

1. A Study of Clinical Outcomes of Ultrasound-guided Carpal Tunnel Release Performed in a Procedural Room Setting

   Albert Lea, Minn.

   The purpose of this study is to document the primary investigator’s clinical experience performing Ultrasound Guided Carpal Tunnel Release (USCTR) in the clinic procedure room setting through retrospective and prospective analysis of these now routinely collected clinical outcomes. 

2. Spinal Cord Injury Physical Activity Guidelines in Association with Health-Related and Psychosocial Outcomes

   Rochester, Minn.

   The purpose of this study is to determine whether meeting the physical activity guidelines for cardiometabolic health is associated with positive health-related outcomes.

   Additionally to determine whether meeting the physical activity guidelines for cardiometabolic health is associated with positive psychosocial outcomes, and determine whether meeting the physical activity guidelines for cardiometabolic health is associated with greater social and occupational integration.  

3. A Study to Evaluate Preventative Saphenous Nerve Neurectomy in Primary Total Knee Arthroplasty

   Jacksonville, Fla.

   The purpose of this study is to evaluate the incidence of chronic knee pain at 6 months following primary total knee arthroplasty. Secondary outcomes include incidence of knee numbness, postoperative sensory loss or change at the knee, range of motion (ROM), resting pain with Visual Analog Scale (VAS), Knee Injury and Osteoarthritis Outcome Score (KOOS), quality of life measurement assessed by SF-36.

4. Facet Joint Articular Cartilage and Disc and Endplate Cartilage Healthy and Degenerated Characterization

   Rochester, Minn.

   The purpose of this study is to determine the biomechanical, biochemical, and histological properties of human spinal cartilage, in both healthy and degenerated patients, and to compare the properties among the different regions of the spine (cervical, thoracic, and lumbar).

5. Knee Biologic Preservation: Functional and Clinical Outcome

   Rochester, Minn.

   The main purpose of this study is to evaluate the clinical and functional outcomes of patients undergoing biologic knee preservation surgery. Secondary purpose is to identify possible correlation between outcome and pre-operative radiological findings (i.e. bony abnormalities such as mal-alignment, size of cartilage defect).

6. A Study To Create A Registry Of Non-Fusion Spinal Deformity Correction In Adolescent Idiopathic Scoliosis

   Minneapolis, Minn., Rochester, Minn.

   The primary purpose of this study is to evaluate the effectiveness of non-fusion surgical treatment of Spinal Deformity Correction in Adolescent Idiopathic Scoliosis.

   The Post Approval Study (PAS) is gathering data on the Tether device and it's efficacy and safety.

7. A Study to Evaluate Outcomes of Pectoralis Minor and Brachial Plexus Release

   Rochester, Minn.

   The purpose of this study is to to assess the clinical and radiographic outcomes of patients who have undergone shoulder arthroplasty.

8. Adult Spinal Deformity Surgery Real-World Functional Activity

   Rochester, Minn.

   The purpose of this study is to measure objective functional activity and gait and trunk stability in spinal deformity patients utilizing motion analysis testing and accelerometers. This will provide real-world data and evidence in optimizing care for spinal deformity patients.

9. Genetic Expression in Osteolysis, Infection, Arthrofibrosis & Metal Reactions in THA & TKA: A Microarray Analysis to Characterize Individual Host Response to the Molecular Mechanisms of Loosening and Arthrofibrosis

   Rochester, Minn.

   This study is being conducted to determine gene and protein expression profiles (i.e. which genes and proteins are turned off and on) of those with a possibility of developing osteolysis, infection, arthrofibrosis or metallosis of their THA/TKA.

10. Early Outcomes of Volar Capsulodesis for the Treatment of Scapholunate Ligament Injury

    Rochester, Minn.

    The purpose of this study is to:

    1. To provide a comprehensive review of Mayo Clinic’s experience with volar SLIL capsulodesis
    2. Investigate the relationships between patient risk factors and clinical variables with functional outcomes and patient satisfaction
    3. Determine rates of complication, revision surgeries and salvage for failure