Orthopedic Surgery

Below are current clinical trials.

Filter this list of studies by location, status and more.

1. A Study to Evaluate Whether Ultrasound Can Detect Medial Meniscal Extrusion More Frequently Than MRI?

   Minneapolis, Minn.

   The purpose of this study is to evaluate whether ultrasound can detect medial meniscal extrusion more frequently than MRI.

2. A Study of Scoliosis Survey to Development Treatment Decision Tool

   Rochester, Minn.

   This is a survey, with the option of uploading prior clinical imaging (x-rays, etc), with the aim to study the burden of scoliosis disease over time and the results of treatment (specifically the results of nonfusion and fusion scoliosis surgery).  Our goal is to report these results back to the community of people with scoliosis and also publish our results in the medical literature.

3. A Study to Evaluate Neurostimulation to Treat Chronic Upper Limb Pain After Brachial Plexus Injury

   Rochester, Minn., Jacksonville, Fla.

   This study is designed to assess the degree to which high-frequency spinal cord stimulation may help with pain after brachial plexus avulsion injury.

4. Analysis of Spinal Cord Stimulation Usage Over a 15-Year Period

   Scottsdale/Phoenix, Ariz., Rochester, Minn.

   The purpose of this study is to determine the rate at which patients who underwent Spinal Cord Stimulation (SCS) trial ultimately progressed to SCS implantation, determine the percentage of patients who continued using their SCS system after 5 years, as well as identify patient characteristics that lead to SCS discontinuation.

5. A Study to Learn More About Characterization of Different Musculoskeletal Tissues

   Rochester, Minn.

   The purpose of this investigation is to characterize the genetic and epigenetic characteristics of different musculoskeletal tissues, as well as their associated disease states. Epigenetic markers represent promising therapeutic targets, as well as diagnostic biomarkers with important clinical utility.

    

6. A Study to Analyze Surgical Outcomes and Predictors of Treatment for Hip Diseases

   Rochester, Minn.

   This study is designed to:
   -analyze effects of surgical treatment
   -improve surgical care and quality of life of patients with hip problems/diseases
   -ID predictors of surgical outcomes to identify/improve future treatments
   -Collect data, images, from patients undergoing surgical treatment of hip disorders (we will not be collecting social security numbers to send to Washington University).

7. A Study to Evaluate Outcomes of Shoulder Arthroplasty

   Rochester, Minn.

   The purpose of this study is to evaluate the outcomes and complications in patients who have received a hemiarthroplasty, anatomic total shoulder, or reverse total shoulder arthroplasty.

    

8. Cutaneous Autonomic Innervation in Skin Pressure Injury Pathophysiology After Spinal Cord Injury

   Rochester, Minn.

   The overall goal of this research is to investigate potential differences in the regulation of skin blood flow in individuals with spinal cord injury.

9. Spatial Profiling of the Zone II (Intrasynovial) Flexor Tendon Fibrotic Niche

   Rochester, Minn.

   The purpose of this study is to compare avian tendon healing spatial biology findings to human intrasynovial tendon tissue spatial gene expression. By correlating findings from our avian tendon repair model to human spatial gene expression findings, a comprehensive spatial molecular atlas or map of the zone II/intrasynovial tendon fibrotic niche could be synthesized. Additionally, by validating the biochemical findings in our avian model, we could further establish this preclinical model as a clinically relevant platform for investigating novel therapeutics to enhance intrinsic healing and mitigate peritendinous adhesions formation following zone II tendon injury.

10. Mayo Clinic Spinal Cord Injury (SCI) Rehabilitation Research Registry

    Rochester, Minn.

    This will be a prospective registry conducted and maintained at Mayo Clinic Rochester from which collaborating sites within Mayo, Mayo Health Systems, and other spinal cord injury centers can draw from in order to fulfill research enrollment. The information collected for this registry will be used for recruitment purposes only, and will not be used as research data. Participants who are recruited to participate in other research studies will need to complete a separate consenting/enrollment process specific to that study.