Precautions

Drug information provided by: Merative, Micromedex®

It is very important that your doctor check your progress at regular visits. This will allow your doctor to see if the medicine is working properly and to decide if you should continue to use it.

This medicine may cause a tear (perforation) in your stomach or bowels. Check with your doctor right away if you have a severe stomach pain that does not go away.

If severe or persistent (non-stop) diarrhea occurs while using methylnaltrexone injection, check with your doctor right away.

Do not suddenly stop using this medicine without checking first with your doctor. Doing so may cause withdrawal symptoms, such as anxiety, chills, increased tearing, redness on the face, neck, arms, and upper chest, feeling cold, diarrhea, irritability, stomach pain, sweating, and yawning.

Do not take other medicines unless they have been discussed with your doctor. This includes prescription or nonprescription (over-the-counter [OTC]) medicines and herbal or vitamin supplements.