Description and Brand Names

Drug information provided by: IBM Micromedex

US Brand Name

  1. Kalydeco


Ivacaftor is used to treat cystic fibrosis (CF) in patients 12 months of age and older. It is only used for patients who have the following mutations in the CF transmembrane conductance regulator (CFTR) gene: G551D, G1244E, G1349D, G178R, G551S, R117H, S1251N, S1255P, S549N, or S549R mutations. Your doctor will use a test to check for the mutation before you receive the medicine. This medicine is a CFTR potentiator, and works by moving more chloride into the cells of your body.

This medicine is available only with your doctor's prescription.

This product is available in the following dosage forms:

  • Tablet
  • Granule