Primary progressive apraxia of speech (PPAOS)

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Displaying 1-5 out of 5 doctors available

  1. Hugo Botha, M.B., Ch.B.

    Hugo Botha, M.B., Ch.B.

    1. Neurologist
    1. Rochester, MN
    Areas of focus:

    Primary progressive apraxia of speech, Dementia, Progressive supranuclear palsy, Alzheimer's disease, Normal pressure h...ydrocephalus, Mild cognitive impairment, Lewy body dementia, Frontotemporal dementia, Vascular dementia, Primary progressive aphasia, Corticobasal degeneration, Semantic dementia

  2. Stuart J. McCarter, M.D.

    Stuart J. McCarter, M.D.

    1. Neurologist
    2. Sleep Medicine Specialist
    1. Rochester, MN
    Areas of focus:

    Polysomnography, Primary progressive apraxia of speech, Narcolepsy, Progressive supranuclear palsy, Alzheimer's disease..., Restless legs syndrome, REM sleep behavior disorder, Mild cognitive impairment, Corticobasal syndrome, Lewy body dementia, Sleep apnea, Frontotemporal dementia, Primary progressive aphasia, Posterior cortical atrophy

  3. Vijay K. Ramanan, M.D., Ph.D.

    Vijay K. Ramanan, M.D., Ph.D.

    1. Neurologist
    1. Rochester, MN
    Areas of focus:

    Primary progressive apraxia of speech, Dementia, Alzheimer's disease, Normal pressure hydrocephalus, Lewy body dementia..., Frontotemporal dementia, Cognitive impairment

  4. Rene L. Utianski, Ph.D., CCC-SLP
    Areas of focus:

    Primary progressive apraxia of speech, Primary progressive aphasia

  5. Meredith R. Wicklund, M.D.

    Meredith R. Wicklund, M.D.

    1. Neurologist
    1. Phoenix, AZ
    Areas of focus:

    Primary progressive apraxia of speech, Dementia, Prion disorders, Creutzfeldt Jakob disease, Alzheimer's disease, Mild ...cognitive impairment, Lewy body dementia, Frontotemporal dementia, Vascular dementia, Primary progressive aphasia, Posterior cortical atrophy, Semantic dementia, Aphasia, Memory loss

Research

Primary Progressive Apraxia of Speech (PPAOS) is a rare, neurodegenerative disorder identified by Mayo Clinic researchers.

Mayo Clinic physician-scientists are working to better understand primary progressive apraxia of speech and related diseases. Their research helps improve how these conditions are diagnosed and treated. Mayo Clinic is a leader in:

  • Describing different types of PPAOS.
  • Finding early signs of disease, called biomarkers, by using advanced brain imaging to support earlier diagnosis and follow changes over time.
  • Using new digital tools, such as artificial intelligence and mobile technology, to help more people get diagnosed sooner.
  • Studying new treatments, such as neuromodulation, to help maintain language and communication skills longer.

Mayo Clinic also takes part in clinical trials to explore new therapies and improve existing treatment options. Talk with your care team about whether a clinical trial may be right for you.

Publications

See a list of publications about primary progressive apraxia of speech by Mayo Clinic doctors on PubMed, a service of the National Library of Medicine.

Research Profiles

By Mayo Clinic Staff

Primary progressive apraxia of speech (PPAOS) care at Mayo Clinic

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Diagnosis & treatmentCare at Mayo Clinic
May 22, 2026
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Primary progressive apraxia of speech (PPAOS)

Research: It's all about patients

[MUSIC PLAYING]

Joseph Sirven, M.D., Professor of Neurology, Mayo Clinic: Mayo's mission is about the patient. The patient comes first. So the mission and research here is to advance how we can best help the patient, how to make sure the patient comes first in care. So in many ways, it's a cycle. It can start with as simple as an idea worked on in a laboratory, brought to the patient bedside, and if everything goes right — and let's say it's helpful or beneficial — then brought on as a standard approach. And I think that is one of the unique characteristics of Mayo's approach to research — that patient-centeredness — that really helps to put it in its own spotlight.