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  1. Hugo Botha, M.B., Ch.B.

    Hugo Botha, M.B., Ch.B.

    1. Neurologist
    1. Rochester, MN
    擅长领域:

    Primary progressive apraxia of speech, Dementia, Progressive supranuclear palsy, Alzheimer's disease, Normal pressure h...ydrocephalus, Mild cognitive impairment, Lewy body dementia, Frontotemporal dementia, Vascular dementia, Primary progressive aphasia, Corticobasal degeneration, Semantic dementia

  2. Stuart J. McCarter, M.D.

    Stuart J. McCarter, M.D.

    1. Neurologist
    2. Sleep Medicine Specialist
    1. Rochester, MN
    擅长领域:

    Polysomnography, Primary progressive apraxia of speech, Narcolepsy, Progressive supranuclear palsy, Alzheimer's disease..., Restless legs syndrome, REM sleep behavior disorder, Mild cognitive impairment, Corticobasal syndrome, Lewy body dementia, Sleep apnea, Frontotemporal dementia, Primary progressive aphasia, Posterior cortical atrophy

  3. Vijay K. Ramanan, M.D., Ph.D.

    Vijay K. Ramanan, M.D., Ph.D.

    1. Neurologist
    1. Rochester, MN
    擅长领域:

    Primary progressive apraxia of speech, Dementia, Alzheimer's disease, Normal pressure hydrocephalus, Lewy body dementia..., Frontotemporal dementia, Cognitive impairment

  4. Rene L. Utianski, Ph.D., CCC-SLP
    擅长领域:

    Primary progressive apraxia of speech, Primary progressive aphasia

  5. Meredith R. Wicklund, M.D.

    Meredith R. Wicklund, M.D.

    1. Neurologist
    1. Phoenix, AZ
    擅长领域:

    Primary progressive apraxia of speech, Dementia, Prion disorders, Creutzfeldt Jakob disease, Alzheimer's disease, Mild ...cognitive impairment, Lewy body dementia, Frontotemporal dementia, Vascular dementia, Primary progressive aphasia, Posterior cortical atrophy, Semantic dementia, Aphasia, Memory loss

研究

Primary Progressive Apraxia of Speech (PPAOS) is a rare, neurodegenerative disorder identified by Mayo Clinic researchers.

Mayo Clinic physician-scientists are working to better understand primary progressive apraxia of speech and related diseases. Their research helps improve how these conditions are diagnosed and treated. Mayo Clinic is a leader in:

  • Describing different types of PPAOS.
  • Finding early signs of disease, called biomarkers, by using advanced brain imaging to support earlier diagnosis and follow changes over time.
  • Using new digital tools, such as artificial intelligence and mobile technology, to help more people get diagnosed sooner.
  • Studying new treatments, such as neuromodulation, to help maintain language and communication skills longer.

Mayo Clinic also takes part in clinical trials to explore new therapies and improve existing treatment options. Talk with your care team about whether a clinical trial may be right for you.

Publications

See a list of publications about primary progressive apraxia of speech by Mayo Clinic doctors on PubMed, a service of the National Library of Medicine.

Research Profiles

May 22, 2026

Primary progressive apraxia of speech (PPAOS)