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Departments that treat this condition Clinical Genomics Gastroenterology and Hepatology Hyperoxaluria Center Liver Transplant Program Nephrology and Hypertension Transplant Center Urology Areas that research this condition Urology Research Doctors who treat this condition Edit search filters close Narrow your search By location Rochester, MN By last name There are no doctors whose last name begins with the letter A A Find a doctor whose last name begins with the letter B B There are no doctors whose last name begins with the letter C C There are no doctors whose last name begins with the letter D D There are no doctors whose last name begins with the letter E E There are no doctors whose last name begins with the letter F F There are no doctors whose last name begins with the letter G G There are no doctors whose last name begins with the letter H H There are no doctors whose last name begins with the letter I I There are no doctors whose last name begins with the letter J J There are no doctors whose last name begins with the letter K K active Find a doctor whose last name begins with the letter L L There are no doctors whose last name begins with the letter M M There are no doctors whose last name begins with the letter N N There are no doctors whose last name begins with the letter O O There are no doctors whose last name begins with the letter P P There are no doctors whose last name begins with the letter Q Q There are no doctors whose last name begins with the letter R R Find a doctor whose last name begins with the letter S S There are no doctors whose last name begins with the letter T T There are no doctors whose last name begins with the letter U U There are no doctors whose last name begins with the letter V V There are no doctors whose last name begins with the letter W W There are no doctors whose last name begins with the letter X X There are no doctors whose last name begins with the letter Y Y There are no doctors whose last name begins with the letter Z Z Reset all filters Search Tips Use quotes for phrases. Even if there are no auto-suggestions within the search field, hit "Search" anyway, as you may still get results. Displaying 1-1 out of 1 doctors available Last Name Initial: L John C. Lieske, M.D. Internist Nephrologist Rochester, MN Areas of focus: Chronic kidney disease, End-stage renal disease, Kidney stone, Hyperoxaluria ResearchMayo Clinic is active in several areas of research on hyperoxaluria, coordinated through the Mayo Clinic Hyperoxaluria Center and the Rare Kidney Stone Consortium in Rochester, Minnesota. The center maintains an international registry of data on people with hyperoxaluria, compiles statistics on outcomes, and maintains a bank of urine, plasma, blood and liver samples for investigation and collaborative research. The center offers people the opportunity to participate in clinical trials, testing new diagnosis and treatment approaches. Ongoing research projects include: Use of active patient registries for primary and enteric hyperoxaluria to improve the understanding of these two diseases. Identification of genetic changes, also called genetic mutations, in primary hyperoxaluria and other genetic causes of kidney stone disease or nephrocalcinosis, including correlation of genetic changes with disease outcomes. Evaluation of new treatments for primary hyperoxaluria, including use of newer agents such as small inhibitory RNAs that block oxalate synthesis in the liver. Evaluation of new treatments for enteric hyperoxaluria, including treatments taken by mouth, also called orally administered, of oxalate-degrading enzymes and bacteria. Evaluation of the effect of diet and calcium intake on urine oxalate levels. Development of new technology for measuring the type of kidney stones on computerized tomography (CT) scans and the ability to fragment them using urologic devices. Improvement of quality of life in patients with primary hyperoxaluria and other people who develop kidney stones. PublicationsSee a list of publications about hyperoxaluria by Mayo Clinic doctors on PubMed, a service of the National Library of Medicine. Research Profiles Edit search filters close Narrow your search By location Arizona Florida Minnesota View all View all physicians • All Locations Harris, Peter C. Ph.D. Minnesota Jayachandran, Muthuvel Ph.D. Minnesota Keddis, Mira T. M.D. Arizona Lieske, John C. M.D. Minnesota Rule, Andrew D. M.D. Minnesota By Mayo Clinic Staff Hyperoxaluria and oxalosis care at Mayo Clinic Request an appointment Diagnosis & treatmentCare at Mayo Clinic May 11, 2023 Print Living with hyperoxaluria and oxalosis? Connect with others like you for support and answers to your questions in the Transplants support group on Mayo Clinic Connect, a patient community. Transplants Discussions Transplant anti-rejection medications. What's your advice? 356 Replies Sat, Oct 26, 2024 chevron-right Liver disease itching: What helps? 157 Replies Fri, Oct 04, 2024 chevron-right Double lung transplant 13 Replies Sun, Sep 15, 2024 chevron-right See more discussions Related Products & Services A Book: Mayo Clinic Family Health Book Newsletter: Mayo Clinic Health Letter — Digital Edition Show more products and services from Mayo Clinic Hyperoxaluria and oxalosisSymptoms&causesDiagnosis&treatmentDoctors&departmentsCare atMayoClinic Research: It's all about patients Show transcript for video Research: It's all about patients [MUSIC PLAYING] Joseph Sirven, M.D., Professor of Neurology, Mayo Clinic: Mayo's mission is about the patient. The patient comes first. So the mission and research here is to advance how we can best help the patient, how to make sure the patient comes first in care. So in many ways, it's a cycle. It can start with as simple as an idea worked on in a laboratory, brought to the patient bedside, and if everything goes right — and let's say it's helpful or beneficial — then brought on as a standard approach. And I think that is one of the unique characteristics of Mayo's approach to research — that patient-centeredness — that really helps to put it in its own spotlight. CON-20166953 Patient Care & Health Information Diseases & Conditions Hyperoxaluria and oxalosis