Print Overview Dupuytren contracture Enlarge image Close Dupuytren contracture Dupuytren contracture Dupuytren contracture is a condition that causes one or more fingers to bend toward the palm of the hand. The affected fingers can't fully straighten. It most often affects the ring finger and little finger. Dupuytren contracture is a condition that makes one or more fingers bend toward the palm of the hand. Over time, the affected fingers can't fully straighten. This happens because tough tissue under the skin of the palm slowly thickens and shortens into cords that pull the fingers down. This condition often gets worse slowly, over years. It most often affects the ring finger and little finger, but any finger or thumb can be affected. The limited motion can make everyday activities difficult. These include putting on gloves, shaking hands and reaching into pockets. There's no cure for Dupuytren contracture. But treatments can relieve symptoms and slow how quickly the condition gets worse.Products & ServicesA Book: Mayo Clinic Family Health BookNewsletter: Mayo Clinic Health Letter — Digital EditionShow more products from Mayo Clinic SymptomsIn Dupuytren contracture, the first symptom typically is a thickening of the skin on the palm of your hand. Over the years, the skin on your palm may look puckered or dimpled, and a firm lump of tissue can form. This lump usually is painless. But sometimes it is painful. Over time, the lump can form a hard cord that extends into the fingers. The finger is pulled into a bent position. Dupuytren contracture typically affects both hands. When to see a doctorSee your healthcare professional if you notice: A lump in your palm that doesn't go away. A finger that starts to bend toward your palm. Trouble placing your hand flat on a table. Difficulty with everyday tasks, such as putting on gloves, shaking hands or reaching into pockets. 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You'll soon start receiving the latest Mayo Clinic health information you requested in your inbox. Sorry something went wrong with your subscription Please, try again in a couple of minutes Retry CausesThe cause of Dupuytren contracture is not known, but it tends to run in families. Risk factorsPeople with certain diseases or health conditions may be more likely to develop Dupuytren contracture. Risk factors include: Age. Dupuytren contracture occurs most commonly after the age of 50. Sex. Men are much more likely to develop Dupuytren than are women. In men, symptoms may be worse and progress more quickly. Ancestry. People of Northern European descent are at higher risk of the disease. Family history. Dupuytren contracture often runs in families. Job. Some studies show a connection between Dupuytren contracture and people who use vibrating tools. Diabetes. People with diabetes have an increased risk of Dupuytren contracture. Tobacco and alcohol use. Smoking tobacco and drinking alcohol have both been linked with an increased risk of Dupuytren contracture in some studies. By Mayo Clinic Staff Request an appointment Diagnosis & treatment May 28, 2026 PrintShow references Frontera WR, et al., eds. Dupuytren contracture. In: Essentials of Physical Medicine and Rehabilitation: Musculoskeletal Disorders, Pain, and Rehabilitation. 4th ed. Elsevier; 2019. https://www.clinicalkey.com. Accessed Aug. 28, 2025. Ferri FF. Dupuytren contracture. In: Ferri's Clinical Advisor 2026. Elsevier; 2026. https://www.clinicalkey.com. Accessed Aug. 28, 2025. Dupuytren contracture. Merck Manual Professional Version. https://www.merckmanuals.com/professional/musculoskeletal-and-connective-tissue-disorders/hand-disorders/dupuytren-contracture?query=dupuytren. Accessed Aug. 28, 2025. Aggarwal R, et al. Dupuytren's contracture. https://www.uptodate.com/contents/search. Accessed Aug 28, 2025. Medical review (expert opinion). Mayo Clinic. Sept. 10, 2025. 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There is a problem with information submitted for this request. Review/update the information highlighted below and resubmit the form. From Mayo Clinic to your inbox Sign up for free and stay up to date on research advancements, health tips, current health topics, and expertise on managing health. Click here for an email preview. Email Address 1 ErrorEmail field is required ErrorInclude a valid email address Learn more about Mayo Clinic’s use of data. We use the data you provide to deliver you the content you requested. To provide you with the most relevant and helpful information, we may combine your email and website data with other information we have about you. If you are a Mayo Clinic patient, we will only use your protected health information as outlined in our Notice of Privacy Practices. You may opt out of email communications at any time by clicking on the unsubscribe link in the email. Subscribe! Thank you for subscribing! You'll soon start receiving the latest Mayo Clinic health information you requested in your inbox. Sorry something went wrong with your subscription Please, try again in a couple of minutes Retry