Cutaneous B-cell lymphoma

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Survival rates

Survival rates are different for each type of cutaneous B-cell lymphoma. They also depend on your overall health, the stage of your cancer and which treatments you are getting. To understand cutaneous B-cell lymphoma survival rates, experts study many people with cutaneous B-cell lymphoma to see how many are living five years after their diagnosis.

The survival rates for each type of cutaneous B-cell lymphoma are:

  • Primary cutaneous follicle center lymphoma. The five-year survival rate for this type is about 95%.
  • Primary cutaneous marginal zone B-cell lymphoma. The five-year survival rate for this type ranges from 98% to 100%.
  • Primary cutaneous diffuse large B-cell lymphoma, leg type. The five-year survival rate for this type ranges from 41% to 66%.
  • Intravascular diffuse large B-cell lymphoma. Current data for this type shows how many people are living three years after their diagnosis. When only in the skin, the three-year survival rate is 56%. If the cancer is present elsewhere in the body, the three-year survival rate is 22%.

Keep in mind that survival statistics take five years to collect. The most recent survival rates include people who had treatment for cutaneous B-cell lymphoma more than five years ago. These people may not have had access to the latest treatments. Over the last few years, survival rates have increased with the addition of new treatments.

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Dec. 12, 2025

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  2. Jacobsen E, et al. Primary cutaneous diffuse large B-cell lymphoma, leg type. https://www.uptodate.com/contents/search. Accessed Oct. 13, 2025.
  3. Jacobsen E, et al. Primary cutaneous follicle center lymphoma. https://www.uptodate.com/contents/search. Accessed Oct. 13, 2025.
  4. Jacobsen E, et al. Primary cutaneous marginal zone lymphoma. https://www.uptodate.com/contents/search. Accessed Oct. 13, 2025.
  5. James WD. Cutaneous lymphoid hyperplasia, lymphoma, and other clonal lymphoid processes. In: Andrews' Diseases of the Skin: Clinical Dermatology. 14th ed. Elsevier; 2025. https://www.clinicalkey.com. Accessed Oct. 13, 2025.
  6. Fletcher CDM. Tumors of the skin. In: Diagnostic Histopathology of Tumors. 5th ed. Elsevier; 2021. https://www.clinicalkey.com. Accessed Oct. 13, 2025.
  7. Vitiello P, et al. Primary cutaneous B-cell lymphomas: An update. Frontiers in Oncology. 2020; doi:10.3389/fonc.2020.00651.
  8. Cancer staging. National Cancer Institute. https://www.cancer.gov/about-cancer/diagnosis-staging/staging. Accessed Oct. 20, 2025.
  9. Paulson CL. Allscripts EPSi. Mayo Clinic. July 15, 2025.

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Cutaneous B-cell lymphoma