Central nervous system lymphoma care at Mayo Clinic

At Mayo Clinic, experts in brain and nervous system conditions, blood cancers and cancer treatment work as a team to care for people with central nervous system (CNS) lymphoma. Your care team will get to know you, help you understand your condition, and create a treatment plan that fits your needs and goals. Mayo Clinic doctors have experience diagnosing and treating rare and complex cancers such as CNS lymphoma.

Your Mayo Clinic care team

People with CNS lymphoma receive care from a team of doctors who are trained to diagnose and treat cancers of the brain, spinal cord and immune system. Your care team may include neuro-oncologists, hematologists, neurosurgeons, ophthalmologists, pathologists and radiologists. Other healthcare professionals, such as rehabilitation specialists, social workers and supportive care professionals, also may be part of your team if needed.

Advanced diagnosis and treatment

Mayo Clinic doctors use advanced imaging, laboratory tests and specialized techniques to diagnose CNS lymphoma accurately. Precise diagnosis helps guide treatment decisions and ensures that you receive the most appropriate care.

People who seek care at Mayo Clinic have access to the full range of treatments for CNS lymphoma. These may include chemotherapy, radiation therapy, targeted therapy, immunotherapy, bone marrow transplant, CAR-T cell therapy and clinical trials. Your care team works closely with you to develop a personalized treatment plan.

Mayo Clinic researchers study new ways to diagnose and treat CNS lymphoma. This research gives you access to promising new therapies and treatment approaches.

Expertise and rankings

Mayo Clinic Comprehensive Cancer Center meets the strict standards for a National Cancer Institute comprehensive cancer center. These standards recognize the center's scientific excellence and multispecialty approach that focuses on cancer prevention, diagnosis and treatment.

Mayo Clinic has been recognized as a top cancer hospital by U.S. News & World Report since it began publishing rankings in 1990. Most recently, Mayo Clinic in Rochester, Minnesota, Mayo Clinic in Jacksonville, Florida, and Mayo Clinic in Phoenix/Scottsdale, Arizona, have been recognized among the top Cancer hospitals in the nation by U.S. News & World Report.

More information about billing and insurance:

Mayo Clinic in Arizona, Florida and Minnesota

Mayo Clinic Health System

April 01, 2026

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