Overview

Adrenoleukodystrophy (uh-dree-noh-loo-koh-DIS-truh-fee) is a type of hereditary (genetic) condition that damages the membrane that insulates nerve cells in your brain (myelin sheath).

In adrenoleukodystrophy (ALD), your body can't break down very long-chain fatty acids (VLCFA), causing saturated VLCFAs to build up in your brain, nervous system and adrenal gland.

Adrenoleukodystrophy care at Mayo Clinic

Dec. 12, 2014
References
  1. NINDS Adrenoleukodystrophy information page. National Institute of Neurological Disorders and Stroke. http://www.ninds.nih.gov/disorders/adrenoleukodystrophy/adrenoleukodystrophy.htm. Accessed Oct. 11, 2014.
  2. X-linked adrenoleukodystrophy. Genetics Home Reference. http://ghr.nlm.nih.gov/condition/x-linked-adrenoleukodystrophy. Accessed Oct. 11, 2014.
  3. Percy AK, et al. Adrenoleukodystrophy. http://www.uptodate.com/home. Accessed Oct. 11, 2014.
  4. Pagon RA, et al. GeneReviews. Seattle, Wash.: University of Washington, Seattle; 2012. http://www.ncbi.nlm.nih.gov/books/NBK1315/. Accessed Oct. 11, 2014.