Research

Nephrology researcher in a lab uses pipette to test samples in a tray. Research improves patient care

Mayo Clinic's world-leading database of kidney samples drives new ways to care for people with kidney disease and high blood pressure.

Our nephrology and hypertension physician-scientists are leaders in research on the causes, prevention and treatment of kidney disease and high blood pressure. They are recognized around the world for improving care and bringing new treatments to patients faster. Mayo Clinic also is home to the Robert M. and Billie Kelley Pirnie Translational Polycystic Kidney Disease (PKD) Center, which focuses on improving care for people with PKD.

Other areas of Mayo Clinic research include:

  • Finding ways to help the heart and kidneys work better in people with long-term heart failure and kidney disease.
  • Studying kidney problems that can happen during pregnancy.
  • Discovering genes that cause polycystic kidney disease in adults and infants.
  • Learning why kidney disease gets worse over time.
  • Understanding how long-term kidney disease increases the risk of heart disease and early death.
  • Studying why calcium builds up in the heart's blood vessels.
  • Exploring how regenerative medicine might help people with long-term kidney disease.
  • Comparing treatments for renal artery disease to see how well they work over time.
  • Studying if checking blood pressure at home improves long-term management of high blood pressure.

Research labs

Explore research labs and Nephrology and Hypertension research areas.

Mayo Nephrology Collaborative Group

Our nephrology and hypertension physician-scientists participate in the Mayo Nephrology Collaborative Group. They work together to design studies to improve the treatment of people with renal parenchymal diseases.

Publications

See a list of publications about nephrology and hypertension by Mayo Clinic authors on PubMed, a service of the National Library of Medicine.

Research Profiles

Dec. 05, 2025