Surgery

Below are current clinical trials.

Filter this list of studies by location, status and more.

1. A Study of Simulated Sylvian Fissure Dissection Under Subarachnoid Hemorrhage Conditions Using a Rodent Microvascular Anastomosis Model

   Rochester, Minn.

   The purpose of this study is to assess the differences in microvascular anastomosis outcomes between the experiment aneurysmal subarachnoid hemorrhage (aSAH)-like conditions and control animals.

2. Investigating the Link Between Type 2 Immunity and NAFLD in Human Obesity- AIM 1

   Scottsdale/Phoenix, Ariz.

   This study is being done to better understand the relationship between inflammation in your AT, abnormal deposition of fat around your liver and how this affects its appearance and function and ultimately insulin resistance.

3. A Study of the Ability to Predict Lymphedema Development Following Axillary Surgery for Breast Cancer and Its Effects on Patient Survivorship

   Jacksonville, Fla.

   The purpose of this study is to better understand the anatomy of the lymphatic structure and the molecular process that leads to the over production of lymph fluid.  This proposal will begin intense lymphedema screening and identify baseline characteristics potentially predisposing someone to lymphedema, and identify molecular markers that might be altered to prevent lymphedema. 

4. Study to Evaluate the Continued Safety and Probable Benefit of the MID-C System for 5 Years Post-Implantation in Adolescent Idiopathic Scoliosis (AIS)

   Rochester, Minn., Minneapolis, Minn.

   The purpose of this study is to evaluate the continued safety and probable benefit of the MID-C system for 5 years post-implantation in Adolescent Idiopathic Scoliosis (AIS).

5. A Study to Evaluate a New Predictive Model for the Progression of Adolescent Idiopathic Scoliosis

   Rochester, Minn.

   The purpose of this study is to characterize the risk of scoliosis progression based on local three-dimensional vertebral and pelvic measurements present on initial evaluation. The proposed new study aims at refining and testing the external validity of this model in a larger cohort. The next step towards using the new model in the clinical setting is to redesign the model and to externally validate the model by measuring the agreement between the new method and the traditional Cobb angle at maturity in a larger multicenter study.  The ultimate goal of this research project will be to validate this new predictive model and finally transfer this new predictive tool in the hands of clinicians treating AIS.

    

6. Study to Validate the Use of a Lymphatic Imaging Protocol to Stage Disease Severity in Patients with Lymphedema

   Jacksonville, Fla.

   The purpose of this study is to validate the use of a lymphatic imaging protocol to stage disease severity in patients with lymphedema and serve as a biomarker for microsurgical treatment response.

7. A Study to Collect Clinical Outcomes of Anatomic and Reverse Total Shoulder Arthroplasty

   Scottsdale/Phoenix, Ariz.

   The purpose of the study is a multi-center prospective registry to collect clinical outcomes of anatomic and reverse total shoulder arthroplasty.

8. A Study to Assess an MRI Image Localizer for 7T MRI Neuronavigation

   Rochester, Minn.

   The purpose of this study is to develop a localizer for use within the 7T MRI to allow for future clinical use in neurosurgical planning.

9. Benevolent Tumor Tissue Repository Fighting for the Legacy of our Young

   Rochester, Minn.

   The aim of this study is to create a patient and patient-advocate catalyzed tumor bank for the retrieval, processing, analysis, and maintenance of pre-treatment, post-treatment and (when available) post-mortem soft tissue sarcoma (STS) tissue and tissue data with an emphasis on STSs occurring in younger patients (YP-STS). This resource-platform will be named Project BTTRFLY (Benevolent Tumor Tissue Repository Fighting for the Legacy of our Young).  

10. A Study to Evaluate Maternal-fetal Immune Responses to Fetal Surgery

    Rochester, Minn.

    The purposes of this study are to determine whether maternal T cells are activated and expand after in utero intervention, and to determine whether placental macrophages and histology in the maternal-fetal interface exhibit increased activation and inflammation in surgical cases born preterm (<37 weeks) compared to term.