Nayantara Coelho-Prabhu, M.B.B.S.

Nayantara Coelho-Prabhu, M.B.B.S., is a gastroenterologist at Mayo Clinic in Rochester, Minnesota. Dr. Coelho-Prabhu specializes in advanced endoscopic procedures for the management of complex gastrointestinal conditions, with particular expertise in precancer and colon cancer in individuals living with inflammatory bowel disease (IBD). She is dedicated to early detection and minimally invasive treatment of precancerous and cancerous lesions, believing that a focused, patient-centered approach improves outcomes and quality of life.

Dr. Coelho-Prabhu trained extensively in the United States, Europe and Japan, gaining advanced skills in complex endoscopic techniques. She works closely with multidisciplinary teams to provide personalized care, combining innovative technology and clinical judgment to address each person's needs.

Areas of expertise

Dr. Coelho-Prabhu focuses on using advanced imaging and therapeutic techniques to manage gastrointestinal diseases and reduce cancer risk. Her clinical expertise includes:

• Inflammatory bowel disease (IBD): Tailored screening and surveillance to reduce colon cancer risk in Crohn's disease and ulcerative colitis.
• Dysplasia in IBD: Early detection and removal of precancerous changes using high-definition imaging and advanced resection methods.
• Colon polyps and precancerous lesions: Advanced endoscopic interventions for complex or high-risk lesions.
• Gastric polyps: Endoscopic management focused on prevention and cancer risk reduction.
• Gastrointestinal bleeding: Endoscopic therapy for acute and chronic bleeding conditions.
• Advanced endoscopic procedures: Endoscopic mucosal resection, endoscopic submucosal dissection, full-thickness resection, suturing techniques, and balloon-assisted enteroscopy.
• Percutaneous feeding tube placement: Endoscopic approaches to nutritional access and support.
• Artificial intelligence in endoscopy: Integrating AI technologies to enhance detection and procedural safety.

Research and professional highlights

Dr. Coelho-Prabhu's research centers on optimizing surveillance and management of dysplasia in IBD and identifying risk factors for colon cancer. She actively studies how artificial intelligence can transform endoscopic practice, improving detection and patient outcomes.

She serves as Chair of the American College of Gastroenterology Practice Parameters Committee and as ACG Governor for Minnesota. Dr. Coelho-Prabhu holds roles on multiple national committees with the AGA, ASGE and ACG, reflecting her leadership in clinical standards and education. She has trained at the National Cancer Center in Japan in advanced endoscopic techniques and currently contributes to curriculum development and hands-on teaching for endoscopic innovation.

Outside of work, she enjoys cooking, traveling, and spending time with her husband, three sons and their goldendoodle.