Yan Bi, M.D., Ph.D.

  1. Gastroenterologist
  2. Internist

Publications

  1. Huang H, Swidnicka-Siergiejko AK, Daniluk J, Gaiser S, Yao Y, Peng L, Zhang Y, Liu Y, Dong M, Zhan X, Wang H, Bi Y, Li Z, Ji B, Logsdon CD. Transgenic Expression of PRSS1R122H Sensitizes Mice to Pancreatitis. Gastroenterology. 2019 Aug 13 [Epub ahead of print]
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  2. Zhan X, Wan J, Zhang G, Song L, Gui F, Zhang Y, Li Y, Guo J, Dawra RK, Saluja AK, Haddock AN, Zhang L, Bi Y, Ji B. Elevated intracellular trypsin exacerbates acute pancreatitis and chronic pancreatitis in mice. Am J Physiol Gastrointest Liver Physiol. 2019 Jun 1; 316 (6):G816-G825 Epub 2019 Apr 03
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  3. Huang H, Chen J, Peng L, Yao Y, Deng D, Zhang Y, Liu Y, Wang H, Li Z, Bi Y, Haddock AN, Zhan X, Lu W, Logsdon CD, Ji B. Transgenic expression of cyclooxygenase-2 in pancreatic acinar cells induces chronic pancreatitis. Am J Physiol Gastrointest Liver Physiol. 2019 Jan 1; 316 (1):G179-G186 Epub 2018 Nov 15
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  4. Zhuang L, Zhan X, Bi Y, Ji B. Induction of Pancreatic Inflammation Accelerates Pancreatic Tumorigenesis in Mice. Methods Mol Biol. 2019; 1882:287-297
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  5. de Pretis N, Mukewar S, Aryal-Khanal A, Bi Y, Takahashi N, Chari S. Pancreatic cysts: Diagnostic accuracy and risk of inappropriate resections. Pancreatology. 2017 Mar - Apr; 17 (2):267-272 Epub 2017 Jan 12
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  6. Zhan X, Wang F, Bi Y, Ji B. Animal models of gastrointestinal and liver diseases. Animal models of acute and chronic pancreatitis. Am J Physiol Gastrointest Liver Physiol. 2016 Sep 1; 311 (3):G343-55 Epub 2016 July 14
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  7. Zhan X, Wang F, Bi Y, Ji B. Animal models of gastrointestinal and liver diseases. animal models of acute and chronic pancreatitis American Journal Of Physiology-Gastrointestinal And Liver Physiology. 2016 Sep 1; 311: (3)G343-55.
  8. Bi Y, Ji B. Spontaneous Pancreatitis in Genetically Modified Animal Strains Pancreapedia: Exocrine Pancreas Knowledge Base .2016;
  9. Bi Y, Hart PA, Law R, Clain JE, Farnell MB, Gleeson FC, Kendrick ML, Levy MJ, Pearson RK, Petersen BT, Pisney LD, Smyrk TC, Takahashi N, Topazian MD, Vege SS, Chari ST. Obstructive jaundice in autoimmune pancreatitis can be safely treated with corticosteroids alone without biliary stenting. Pancreatology. 2016 May-Jun; 16: (3)391-6.
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  10. Bi Y, Atwal T, Vege SS. Drug Therapy for Acute Pancreatitis. Curr Treat Options Gastroenterol. 2015 Sep; 13 (3):354-68
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  11. Vege SS, Atwal T, Bi Y, Chari ST, Clemens MA, Enders FT. Pentoxifylline Treatment in Severe Acute Pancreatitis: A Pilot, Double-Blind, Placebo-Controlled, Randomized Trial. Gastroenterology. 2015 Aug; 149 (2):318-20.e3 Epub 2015 June 23
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  12. Hart PA, Baichoo E, Bi Y, Hinton A, Kudva YC, Chari ST. Pancreatic polypeptide response to a mixed meal is blunted in pancreatic head cancer associated with diabetes mellitus. Pancreatology. 2015 Mar-Apr; 15: (2)162-6.
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  13. Simonetto DA, Yang HY, Yin M, de Assuncao TM, Kwon JH, Hilscher M, Pan S, Yang L, Bi Y, Beyder A, Cao S, Simari RD, Ehman R, Kamath PS, Shah VH. Chronic passive venous congestion drives hepatic fibrogenesis via sinusoidal thrombosis and mechanical forces. Hepatology. 2015 Feb; 61 (2):648-59 Epub 2015 Jan 05
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  14. Bi Y, Mukhopadhyay D, Drinane M, Ji B, Li X, Cao S, Shah VH. Endocytosis of collagen by hepatic stellate cells regulates extracellular matrix dynamics. Am J Physiol Cell Physiol. 2014 Oct 1; 307 (7):C622-33 Epub 2014 July 30
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  15. Bi Y, Li J, Ji B, Kang N, Yang L, Simonetto DA, Kwon JH, Kamath M, Cao S, Shah V. Sphingosine-1-phosphate mediates a reciprocal signaling pathway between stellate cells and cancer cells that promotes pancreatic cancer growth. Am J Pathol. 2014 Oct; 184 (10):2791-802 Epub 2014 Aug 08
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  16. Yang L, Kwon J, Popov Y, Gajdos GB, Ordog T, Brekken RA, Mukhopadhyay D, Schuppan D, Bi Y, Simonetto D, Shah VH. Vascular endothelial growth factor promotes fibrosis resolution and repair in mice. Gastroenterology. 2014 May; 146 (5):1339-50.e1 Epub 2014 Feb 04
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  17. Bi Y, Venkatesh SK, Shah VH. Detecting fibrosis without a liver biopsy: getting to the fat of the issue. Hepatol Int. 2013 Jul; 7 (3):792-4 Epub 2013 July 18
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  18. Sabbatini ME, Bi Y, Ji B, Ernst SA, Williams JA. CCK activates RhoA and Rac1 differentially through Galpha13 and Galphaq in mouse pancreatic acini. Am J Physiol Cell Physiol. 2010 Mar; 298: (3)C592-601.
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  19. Ji B, Tsou L, Wang H, Gaiser S, Chang DZ, Daniluk J, Bi Y, Grote T, Longnecker DS, Logsdon CD. Ras activity levels control the development of pancreatic diseases. Gastroenterology. 2009 Sep; 137: (3)1072-82, 1082.e1-6.
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  20. Boonyaratanakornkit V, Bi Y, Rudd M, Edwards DP. The role and mechanism of progesterone receptor activation of extra-nuclear signaling pathways in regulating gene transcription and cell cycle progression. Steroids. 2008 Oct; 73: (9-10)922-8.
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  21. Ji B, Song J, Tsou L, Bi Y, Gaiser S, Mortensen R, Logsdon C. Robust acinar cell transgene expression of CreErT via BAC recombineering. Genesis. 2008 Aug; 46: (8)390-5.
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  22. Bi Y, Page SL, Williams JA. Rho and Rac promote acinar morphological changes, actin reorganization, and amylase secretion. Am J Physiol Gastrointest Liver Physiol. 2005 Sep; 289: (3)G561-70.
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  23. Bi Y, Williams JA. A role for Rho and Rac in secretagogue-induced amylase release by pancreatic acini. Am J Physiol Cell Physiol. 2005 Jul; 289: (1)C22-32.
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  24. Bi Y, Williams JA. Receptor biology and signal transduction in pancreatic acinar cells. Curr Opin Gastroenterol. 2004 Sep; 20: (5)427-34.
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  25. Le Page SL, Bi Y, Williams JA. CCK-A receptor activates RhoA through G alpha 12/13 in NIH3T3 cells. Am J Physiol Cell Physiol. 2003 Nov; 285: (5)C1197-206.
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  26. Ji B, Bi Y, Simeone D, Mortensen RM, Logsdon CD. Human pancreatic acinar cells do not respond to cholecystokinin. Pharmacol Toxicol. 2002 Dec; 91: (6)327-32.
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  27. Ji B, Bi Y, Simeone D, Mortensen RM, Logsdon CD. Human pancreatic acinar cells lack functional responses to cholecystokinin and gastrin. Gastroenterology. 2001 Dec; 121: (6)1380-90.
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PST-20215940