Nathaniel E. Wiest, M.D., Ph.D.

Nathaniel Wiest, M.D., Ph.D., is a medical oncologist and physician-scientist specializing in the treatment of breast cancer. He provides care as part of a multidisciplinary team that includes surgeons, radiation oncologists, radiologists, pathologists, genetic counselors, internists, dermatologists, and supportive care specialists. Dr. Wiest works with each patient to develop an individualized treatment plan that reflects their goals, values, and preferences.

Dr. Wiest's clinical interests include:

• Multidisciplinary management of breast cancer
• Precision‑medicine approaches informed by biomarker and genomic testing
• Engagement with clinical trials and emerging therapies
• Personalized care that supports both quality and quantity of life

In addition to his clinical practice, Dr. Wiest is active in translational research. He has a background in molecular genetics with a focus on DNA repair biology. His research incorporates studying the biology and treatment of DNA repair‑deficient cancers, including BRCA1/2‑associated breast cancers, and developing novel targeted therapies.