Ulcerative colitis affects about the same number of women and men. Risk factors may include:
Sep. 09, 2014
- Age. Ulcerative colitis usually begins before the age of 30. But, it can occur at any age, and some people may not develop the disease until after age 60.
- Race or ethnicity. Although whites have the highest risk of the disease, it can occur in any race. If you're of Ashkenazi Jewish descent, your risk is even higher.
- Family history. You're at higher risk if you have a close relative, such as a parent, sibling or child, with the disease.
- Isotretinoin use. Isotretinoin (Amnesteem, Claravis, Sotret; formerly Accutane) is a medication sometimes used to treat scarring cystic acne or acne. Some studies suggest it is a risk factor for IBD, but a clear association between ulcerative colitis and isotretinoin has not been established.
- Ulcerative colitis. National Institute of Diabetes and Digestive and Kidney Diseases. http://digestive.niddk.nih.gov/ddiseases/pubs/colitis/. Accessed June 16, 2014.
- Ulcerative colitis. The Merck Manual for Health Care Professionals. http://www.merckmanuals.com/professional/print/sec02/ch018/ch018c.html. Accessed June 16, 2014.
- What is ulcerative colitis? Crohn's and Colitis Foundation of America. http://www.ccfa.org/what-are-crohns-and-colitis/what-is-ulcerative-colitis/. Accessed June 16, 2014.
- Barrett KE, et al. Pharmacological aspects of therapy in inflammatory bowel diseases: Antidiarrheal agents. Journal of Clinical Gastroenterology. 1988;10:57.
- Dignass A, et al. Second European evidence-based consensus on the diagnosis and management of ulcerative colitis part 1: Definitions and diagnosis. Journal of Crohn's and Colitis. 2012;6:965.
- Peppercorn MA, et al. Clinical manifestations, diagnosis, and prognosis of ulcerative colitis in adults. http://www.uptodate.com/home. Accessed June 16, 2014.
- Sandborn WJ, et al. Colectomy rate comparison after treatment of ulcerative colitis with placebo or infliximab. Gastroenterology. 2009;137:1250.
- Kornbluth A, et al. Ulcerative colitis practice guidelines in adults: American College of Gastroenterology, Practice Parameters Committee. American Journal of Gastroenterology. 2010;105:501.
- Dignass A, et al. Second European evidence-based consensus on the diagnosis and management of ulcerative colitis part 2: Current management. Journal of Crohn's and Colitis. 2012;6:991.
- Carter MJ, et al. Guidelines for the management of inflammatory bowel disease in adults. Gut. 2004;53:v1.
- Cohen RD, et al. Approach to adults with steroid-refractory and steroid-dependent ulcerative colitis. http://www.uptodate.com/home. Accessed July 7, 2014.
- Inflammatory bowel disease. U.S. Centers for Disease Control and Prevention. http://www.cdc.gov/ibd/. Accessed June 9, 2014.
- Golden AK. Decision Support System. Mayo Clinic, Rochester, Minn. June 16, 2014.
- Colorectal cancer screening guidelines. U.S. Centers for Disease Control and Prevention. http://www.cdc.gov/cancer/colorectal/basic_info/screening/guidelines.htm. Accessed July 12, 2011.
- Living with Crohn's and Colitis. Crohn's and Colitis Foundation of America. http://www.ccfa.org/living-with-crohns-colitis/. Accessed June 2, 2014.
- What is complementary and alternative medicine (CAM)? International Foundation for Functional Gastrointestinal Disorders. http://www.iffgd.org/store/viewproduct/700. Accessed June 25, 2014.
- Sartor RB. Probiotics for gastrointestinal diseases. http://www.uptodate.com/home. Accessed June 10, 2014.
- Rakel D. Integrative Medicine. 3rd ed. Philadelphia, Pa.: Saunders Elsevier; 2012. http://www.clinicalkey.com. Accessed June 4, 2014.
- U.S. News best hospitals 2013-2014. U.S. News & World Report. http://health.usnews.com/best-hospitals/rankings/gastroenterology-and-gi-surgery. Accessed July 5, 2014.
- Etminan M, et al. Isotretinoin and risk for inflammatory bowel disease: A nested case-control study and meta-analysis of published and unpublished data. JAMA Dermatology. 2013;149:216.
- Leong RW, et al. Implementation of image enhanced endoscopy into solo and group practices for dysplasia detection in Crohn's disease and ulcerative colitis. Gastrointestinal Endoscopy Clinics of North America. 2014;24:419.
- Picco MF (expert opinion). Mayo Clinic, Jacksonville, Fla. July 12, 2014.
- Bruining DH, et al. Technology insight: New techniques for imaging the gut in patients with IBD. Nature Clinical Practice Gastroenterology & Hepatology. 2008;5:154.
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