While any type of infection — bacterial, viral or fungal — can lead to sepsis, the most likely varieties include:
- Abdominal infection
- Kidney infection
- Bloodstream infection (bacteremia)
The incidence of sepsis appears to be increasing in the United States. The causes of this increase may include:
July 23, 2014
- Aging population. Americans are living longer, which is swelling the ranks of the highest risk age group — people older than 65.
- Drug-resistant bacteria. Many types of bacteria can resist the effects of antibiotics that once killed them. These antibiotic-resistant bacteria are often the root cause of the infections that trigger sepsis.
- Weakened immune systems. More Americans are living with weakened immune systems, caused by HIV, cancer treatments or transplant drugs.
- Maloney PJ. Sepsis and septic shock. Emergency Medicine Clinics of North America. 2013;31:583.
- McKean SC, et al. Principles and Practice of Hospital Medicine. New York, N.Y.: The McGraw-Hill Companies; 2012. http://www.accessmedicine.com/resourceTOC.aspx?resourceID=749. Accessed May 27, 2014.
- Tintinalli JE, et al. Tintinalli's Emergency Medicine: A Comprehensive Study Guide. 7th ed. New York, N.Y.: The McGraw Hill Companies; 2011. http://www.accessmedicine.com/resourceTOC.aspx?resourceID=40. Accessed May 27, 2014.
- Neviere R. Sepsis and the systemic inflammatory response syndrome: Definitions, epidemiology, and prognosis. http://www.uptodate.com/home. Accessed May 28, 2014.
- Angus DC, et al. Severe sepsis and septic shock. New England Journal of Medicine. 2013;369:840.
- Mandell GL, et al. Mandell, Douglas, and Bennett's Principles and Practice of Infectious Diseases. 7th ed. Philadelphia, Pa.: Churchill Livingstone Elsevier; 2010. https://www.clinicalkey.com. Accessed May 27, 2014.