Complications of Rett syndrome include:

  • Movement problems (motor dysfunction), such as irregular hand movements and difficulty walking
  • Unusual sleep patterns — such as falling asleep during the day or waking up at night
  • Seizures
  • Difficulty eating, leading to poor nutrition and delayed growth
  • Constipation, which can be a severe and long-term, ongoing problem
  • Life-threatening heart rhythms (cardiac dysrhythmias)
  • Thin, fragile bones prone to fractures
  • Scoliosis (abnormal curvature of the spine), which may require surgery if it's severe
  • Shortened life span — people with Rett syndrome don't live as long as most people because of heart problems and other health complications
Oct. 04, 2012