Complications of Rett syndrome include:

  • Needing lifelong care and assistance with activities of daily living
  • Sleep problems, including unusual sleep patterns such as falling asleep during the day or waking up at night
  • Difficulty eating, leading to poor nutrition and delayed growth
  • Constipation, which can be a severe, ongoing problem, as well as other gastrointestinal (GI) problems, such as gastroesophageal reflux disease (GERD)
  • Muscle and joint problems
  • Anxiety and problem behavior that may compromise social functioning
  • Shortened life span — people with Rett syndrome don't live as long as most people because of heart problems and other health complications
Sept. 17, 2015