Ewing's sarcoma is a type of cancer that occurs most often in and around the bones. Ewing's sarcoma is rare and typically affects children and young adults, though it can occur at any age.

Ewing's sarcoma can occur in any bone, but most often begins in the leg bones and hipbones, as well as the bones in the arms, chest, skull and spine. Ewing's sarcoma rarely occurs in the soft tissues of the arms, legs, abdomen, chest, neck and head.

Read more about bone cancer.

  • Teamwork. At Mayo Clinic, orthopedic oncologists work with medical oncologists, pediatric oncologists, surgical oncologists, radiation oncologists, pathologists and rehabilitation specialists to care for people with Ewing's sarcoma. Other professionals are included as needed.
  • Experience. Ewing's sarcoma is an uncommon type of cancer. Mayo Clinic doctors have extensive experience diagnosing and treating Ewing's cancer.
  • A full range of treatment options to consider. Mayo Clinic doctors will work with you to review all of your treatment options and choose the treatment that best suits your needs and goals. The range of treatments offered to people with Ewing's sarcoma includes chemotherapy, radiation and surgery.
  • Comprehensive cancer center. Mayo Clinic Cancer Center meets strict standards for a National Cancer Institute comprehensive cancer center, which recognizes scientific excellence and a multidisciplinary approach to cancer prevention, diagnosis and treatment.

Mayo Clinic in Rochester, Minn., and Mayo Clinic in Scottsdale, Ariz., are ranked among the Best Hospitals for cancer by U.S. News & World Report. Mayo Clinic in Jacksonville, Fla., is ranked high performing for cancer by U.S. News & World Report.

At Mayo Clinic, we assemble a team of specialists who take the time to listen and thoroughly understand your health issues and concerns. We tailor the care you receive to your personal health care needs. You can trust our specialists to collaborate and offer you the best possible outcomes, safety and service.

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Treatment for Ewing's sarcoma may include:

  • Chemotherapy. Chemotherapy uses drugs to kill cancer cells. Doctors often recommend chemotherapy before surgery to shrink Ewing's sarcoma tumors and make them easier to remove. Chemotherapy may continue after surgery to kill any cancer cells that might remain in the body.
  • Radiation therapy. Radiation therapy uses high-energy beams, such as X-rays, to kill cancer cells. Radiation therapy may be used after surgery to kill any cancer cells that remain. Radiation therapy can also be used instead of surgery if your Ewing's sarcoma is located in a part of your body that makes surgery risky or difficult. Radiation therapy is also used to relieve pain caused by Ewing's sarcoma.
  • Surgery. The goal of surgery is to remove the cancer cells, but surgeons also perform operations to maintain function and minimize disability. Surgery for Ewing's sarcoma may involve removing a small portion of bone or removing an entire limb.

    Mayo Clinic has significant experience in limb-saving techniques, and if the tumor involves an arm or leg, most of the time the limb can be saved. The possibility of saving the limb depends on several factors, such as the tumor's size, location and its response to chemotherapy.

Mayo Clinic works with hundreds of insurance companies and is an in-network provider for millions of people. In most cases, Mayo Clinic doesn't require a physician referral. Some insurers require referrals or may have additional requirements for certain medical care. All appointments are prioritized on the basis of medical need.

Specialists in orthopedic surgery, oncology, radiation oncology, pathology, physical medicine and rehabilitation, and general surgery at Mayo Clinic in Arizona care for adults who have Ewing's sarcoma.

For appointments or more information, call the Central Appointment Office at 800-446-2279 (toll-free) 8 a.m. to 5 p.m. Mountain Standard Time, Monday through Friday or complete an online appointment request form.

Specialists in orthopedic surgery, oncology, radiation oncology, pathology, physical medicine and rehabilitation, and general surgery at Mayo Clinic in Florida care for adults with Ewing's sarcoma. The team also may include specialists in plastic surgery and vascular surgery.

For appointments or more information, call the Central Appointment Office at 904-953-0853 8 a.m. to 5 p.m. Eastern time, Monday through Friday or complete an online appointment request form.

Specialists in pediatric oncology, general surgery, medical oncology, radiation oncology, pathology and orthopedic oncology care for children and adults with Ewing's sarcoma.

For appointments or more information, call the Central Appointment Office at 507-538-3270 7 a.m. to 6 p.m. Central time, Monday through Friday or complete an online appointment request form.

See information on patient services at the three Mayo Clinic locations, including transportation options and lodging.

Mayo Clinic doctors and researchers are investigating new ways to diagnose and treat Ewing's sarcoma.

Cancer research is conducted in coordination with the Mayo Clinic Cancer Center. The Mayo Clinic Cancer Center receives funding from the National Cancer Institute and is designated as a comprehensive cancer center — recognition for an institution's scientific excellence and multidisciplinary resources focused on cancer prevention, diagnosis and treatment.

Publications

See a list of publications by Mayo Clinic authors on Ewing's sarcoma on PubMed, a service of the National Library of Medicine.

Jun. 06, 2014