Stages If you're diagnosed with peripheral T-cell lymphoma (PTCL), the next step is to find out how much and where the cancer has spread. This is called the stage. Healthcare professionals may use imaging and biopsies to determine the stage by looking at how big the cancer is, its location and the distance it has traveled from where it first started. Your healthcare team creates your treatment plan based on the stage. A higher stage number means the cancer is more advanced. The stages of PTCL typically range from 1 to 4: Stage 1. The cancer typically affects a single lymph node area or extranodal lesion, which means an area beyond the lymph node. Stage 2. The cancer involves two or more lymph node areas on the same side of the diaphragm. Stage 3. The cancer is more advanced and involves lymph nodes above and below the diaphragm or lymph nodes above the diaphragm and involving the spleen. Stage 4. The cancer has traveled outside of the lymph nodes and may reach organs including the liver, spleen, skin, GI tract and bone marrow. Some PTCL subtypes have a bulky stage. Bulky means a large mass, usually around 4 inches (10 cm). 申请预约 诊断与治疗医生与科室 April 10, 2026 显示参考文献 T-cell lymphomas. National Comprehensive Cancer Network. https://www.nccn.org. Accessed Dec. 30, 2025. Peripheral T-cell non-Hodgkin lymphoma treatment (PDQ) — Health professional version. National Cancer Institute. https://www.cancer.gov/types/lymphoma/hp/peripheral-t-cell-lymphoma-pdq. Accessed Dec. 30, 2025. Freedman A, et al. Clinical manifestations, pathologic features, and diagnosis of peripheral T-cell lymphoma, not otherwise specified. https://www.uptodate.com/contents/search. Accessed Dec. 30, 2025. Jacobson E, et al. Initial treatment of peripheral T cell lymphoma. https://www.uptodate.com/contents/search. Accessed Dec. 30, 2025. Jacobson E. Treatment of relapsed or refractory peripheral T cell lymphoma. https://www.uptodate.com/contents/search. Accessed Dec. 30, 2025. Elsevier Point of Care. Clinical Overview: Peripheral T-cell lymphoma. https://www.clinicalkey.com. Accessed Dec. 30, 2025. Hoffman R, et al. T-cell lymphoma. In: Hematology: Basic Principles and Practice. 8th ed. Elsevier; 2023. https://www.clinicalkey.com. Accessed Jan. 5, 2026. Jaffe ES, et al., eds. Hematopathology. 3rd ed. Elsevier; 2025. https://www.clinicalkey.com. Accessed Feb. 17, 2026. Goldman L, et al, eds. Non-Hodgkin lymphomas. In: Goldman-Cecil Medicine. 27th ed. Elsevier; 2024. https://www.clinicalkey.com. Accessed Feb. 17, 2026. Paulson CL. Allscripts EPSi. Mayo Clinic. July 15, 2025. Peripheral T-cell lymphoma症状与病因诊断与治疗Stages医生与科室在 Mayo Clinic 治疗 CON-20592494 疾病与状况 Peripheral T-cell lymphoma