Treatment of leiomyosarcoma depends on where the cancer is, how big it is and whether it has spread to other areas of the body. Your overall health and what you want also are part of the treatment plan.

Surgery

The goal of surgery is to remove all the leiomyosarcoma. But that might not be possible if the cancer is large or involves nearby organs. Then your surgeon may remove as much of the cancer as possible.

Radiation therapy

Radiation therapy treats cancer with powerful energy beams. The energy can come from X-rays, protons or other sources.

Radiation therapy can be used before, after or during surgery. It can treat cancer cells that can't be removed during surgery. Radiation therapy also might be used when surgery isn't an option.

Chemotherapy

Chemotherapy treats cancer with strong medicines. Most chemotherapy medicines are given through a vein.

Healthcare professionals might suggest chemotherapy to prevent the leiomyosarcoma from returning after surgery. It also might be used to control cancer that spreads to other areas of the body.

Targeted therapy

Targeted therapy for cancer is a treatment that uses medicines that attack specific chemicals in the cancer cells. By blocking these chemicals, targeted treatments can cause cancer cells to die.

Targeted therapy may be an option for leiomyosarcoma that grows large or spreads to other parts of the body. Your healthcare professional may test your cancer cells to see if targeted medicines might help you.