Treatment Print There's no cure for Kaposi sarcoma. But there are many treatment options that can help control it. Some people may not need treatment right away. Instead, the condition might be monitored to make sure it's not getting worse. Treatment depends on: The type of Kaposi sarcoma. The number of lesions and where they are. The effects of the lesions, such as causing pain or getting in the way of eating or breathing. Your overall health. Treatment for AIDS-related Kaposi sarcomaThanks to better antiviral medicines to treat AIDS and ways to prevent it, Kaposi sarcoma has become less common and less severe in people with AIDS. Taking antiviral medicines can lower the amount of the virus that causes HIV/AIDS and make the immune system stronger. This might be the only treatment needed for Kaposi sarcoma. Treatment for transplant-related Kaposi sarcomaSome people with transplant-related Kaposi sarcoma may be able to stop taking the medicines that are controlling the immune system or switch to another medicine. Treatment for small skin lesionsTreatments for small skin lesions might include: Minor surgery, also called excision. Freezing treatment, called cryotherapy. Radiation therapy. An injection of the chemotherapy medicine vinblastine into lesions. Applying a medicine cream or gel to the skin. Lesions treated in any of these ways are likely to return within a couple of years. When this happens, treatment often can be repeated. Treatment if there are many skin lesionsIf Kaposi sarcoma causes many skin lesions, other treatments might be needed, such as: Radiation therapy. Radiation therapy uses powerful energy beams to kill cancer cells. This is a treatment option if there are many skin lesions, but not enough to need chemotherapy. Chemotherapy. Chemotherapy uses strong medicines to kill cancer cells. Chemotherapy might be an option when Kaposi sarcoma affects multiple parts of the body. For Kaposi sarcoma that's getting worse quickly, chemotherapy might help. Print Share on: FacebookTwitter Advertisement Mayo Clinic does not endorse companies or products. Advertising revenue supports our not-for-profit mission. Advertising & Sponsorship Policy Opportunities Ad Choices Mayo Clinic Press Check out these best-sellers and special offers on books and newsletters from Mayo Clinic Press. NEW: Mayo Clinic Guide to Better Sleep Listen to Health Matters Podcast Mayo Clinic on Incontinence The Essential Diabetes Book FREE Mayo Clinic Diet Assessment Mayo Clinic Health Letter - FREE book Home Treatment