Print By Mayo Clinic Staff Request an appointment About Oct. 13, 2023 Print Show references Siderowf A, et al. Assessment of heterogeneity among participants in the Parkinson's Progression Markers Initiative cohort using alpha-synuclein seed amplification: A cross-sectional study. The Lancet Neurology. 2023; doi:10.1016/S1474-4422(23)00109-6. Berg D, et al. Alpha-synuclein seed amplification and its uses in Parkinson's disease. The Lancet Neurology. 2023; doi:10.1016/S1474-4422(23)00124-2. Parkinson's disease: Hope through research. National Institute of Neurological Disorders and Stroke. https://www.ninds.nih.gov/Disorders/Patient-Caregiver-Education/Hope-Through-Research/Parkinsons-Disease-Hope-Through-Research. Accessed July 13, 2023. CSF analysis. Lab Tests Online. https://www.testing.com/tests/cerebrospinal-fluid-csf-testing/. Accessed July 14, 2023. Grossauer A, et al. a-Synuclein seed amplification assays in the diagnosis of synucleinopathies using cerebrospinal fluid — A systematic review and meta-analysis. Movement Disorders Clinical Practice. 2023; doi:10.1002/mdc3.13710. Bellomo G, et al. a-Synuclein seed amplification assays for diagnosing synucleinopathies: The way forward. Neurology. 2022; doi:10.1212/WNL.0000000000200878. Lumbar puncture. Radiological Society of North America. https://www.radiologyinfo.org/en/info/SpinalTap. Accessed July 14, 2023. Johnson KS, et al. Lumbar puncture: Technique, indications, contraindications, and complications in adults. https://www.uptodate.com/contents/search. Accessed July 14, 2023. Related Lumbar puncture (spinal tap) Parkinson's disease Parkinson's test (a-Synuclein seed amplification assay)About PRC-20548298 Patient Care & Health Information Tests & Procedures Parkinson's test