Mayo Clinic's approach


The Transgender and Intersex Specialty Care Clinic (TISCC) provides integrated medical, psychosocial and surgical intervention to individuals with gender dysphoria/incongruence and to those with differences of sexual development (intersex). The team includes providers from various specialties including endocrinology, pediatric endocrinology, social work, psychiatry, psychology, voice therapy, gynecology and plastic surgery.

Treatments offered include:

  • Mental health assessment and management
  • Hormone therapy and monitoring
  • Assistance with social and legal issues and referrals to community resources
  • Fertility preservation
  • Sexually transmitted infection screening and preexposure prophylaxis (PrEP)
  • Voice therapy
  • Electrolysis and laser hair removal
  • Hair transplant
  • Gynecological care for trans men
  • Chaplain services
  • Feminizing surgical procedures:
    • Top surgery for transgender women
    • Facial feminization
    • Body-contouring procedures
    • Orchiectomy
    • Tracheal shave
    • Penile inversion vaginoplasty
  • Masculinizing surgical procedures:
    • Top surgery for transgender men and nonbinary people
    • Body-contouring procedures
    • Hysterectomy/oophorectomy
  • Preoperative and postoperative pelvic floor physical therapy

Before you start treatment, you will meet with at least one member of the TISCC medical team — a doctor or nurse practitioner — and a member of the TISCC behavioral health team, such as a social worker or psychologist. You'll have a complete medical evaluation to make sure that your treatment risks are identified and addressed. Before a surgical procedure, you will be seen by the appropriate TISCC surgical team. Evaluation of your mental health ensures that any mood or mental health concerns are reasonably well managed before you start treatment.

Each person is different. Your providers will look at your specific case in order to come up with the best recommendations for you. Your health care team will work with you during your treatment and make sure your expectations are realistic. Your team wants to make sure your goals are being met, any risks are managed and your questions are answered.

Advanced technology

Mayo Clinic specialists are committed to providing the latest, most comprehensive treatment options for gender dysphoria/incongruence. Your Mayo Clinic specialist's advice about the best treatment for you will be based on expert knowledge of and experience with all treatment options for gender dysphoria.

Expertise and rankings

At Mayo Clinic, endocrinologists, psychiatrists, psychologists, nurse practitioners, social workers and surgeons work together to provide exactly the care you need.

Having all of this expertise in a single place, focused on you, means that you're not just getting one opinion — your care is discussed among the team, your test results are available quickly, your appointments are scheduled in coordination, and highly specialized experts are all working together to determine what's best for you.

Locations, travel and lodging

Mayo Clinic has major campuses in Phoenix and Scottsdale, Arizona; Jacksonville, Florida; and Rochester, Minnesota. The Mayo Clinic Health System has dozens of locations in several states.

For more information on visiting Mayo Clinic, choose your location below:

Costs and insurance

Mayo Clinic works with hundreds of insurance companies and is an in-network provider for millions of people.

In most cases, Mayo Clinic doesn't require a physician referral. Some insurers require referrals, or may have additional requirements for certain medical care. All appointments are prioritized on the basis of medical need.

Learn more about appointments at Mayo Clinic.

Please contact your insurance company to verify medical coverage and to obtain any needed authorization prior to your visit. Often, your insurer's customer service number is printed on the back of your insurance card.

More information about billing and insurance:

Mayo Clinic in Arizona, Florida and Minnesota

Mayo Clinic Health System

Clinical trials

Explore Mayo Clinic studies of tests and procedures to help prevent, detect, treat or manage conditions.

Feb. 21, 2023
  1. Ferrando C, et al. Transgender surgery: Male to female. Accessed Nov. 3, 2021.
  2. Schechter LS, ed. Surgical therapy for transwomen. In: Surgical Management of the Transgender Patient. Elsevier; 2017. Accessed Nov. 3, 2021.
  3. Coleman E, et al. Surgery. In: Standards of Care for the Health of Transsexual, Transgender and Gender Nonconforming People. 7th version. World Professional Association for Transgender Health; 2012. Accessed Nov. 3, 2021.
  4. AskMayoExpert. Gender-affirming procedures (adult). Mayo Clinic; 2021.
  5. Siringo NV, et al. Techniques and trends of facial feminization surgery: A systematic review and representative case report. Annals of Plastic Surgery. 2021; doi:10.1097/SAP.0000000000002952.
  6. Baker SB, et al., eds. Facial feminization surgery. In: Aesthetic Surgery of the Facial Skeleton. Elsevier; 2022. Accessed Nov. 5, 2021.
  7. Ferrando CA. Facial feminization surgery and facial gender confirmation surgery. In: Comprehensive Care of the Transgender Patient. Elsevier; 2020. Accessed Nov. 5, 2021.
  8. Dang BN, et al. Evaluation and treatment of facial feminization surgery: Part II. lips, midface, mandible, chin, and laryngeal prominence. Archives of Plastic Surgery. 2022; doi:10.5999/aps.2021.01956.
  9. Kotha VS, et al. Simultaneous zygomatic osteotomies with reduction mandibuloplasty - An approach to mid- and lower-facial feminization in the transfeminine patient. The Journal of Craniofacial Surgery. 2021; doi:10.1097/SCS.0000000000008386.


Products & Services

Facial feminization surgery